| Type | Description |
|---|---|
| Definition | polyhomeotic 2 |
| Date | Results | Publications |
|---|---|---|
| 2019-12-21 10:50:00 | Study demonstrates that Phc2 regulates hematopoietic stem and progenitor cells mobilization through the repression of Vcam1 expression by enhancing both H3K27me3 and H2AK119ub in bone marrow stromal cells. | 31375680 |
| 2013-12-07 11:27:00 | polymerization of the Phc2 SAM domain is required for PRC1 clustering, chromatin condensation and gene silencing. | 24091011 |
| 2013-12-07 10:49:00 | Phc2 may act as a negative regulator that inhibits the activity of Th cells. | 23605804 |
| 2010-01-21 00:00:00 | Mph2 is expressed in the ventricular zones of the cortex and ganglionic eminences as well as in mature structures such as the granule cell layer of the adult dentate gyrus and cerebellum; it has roles in both the developing and adult brain | 15580621 |
| 2010-01-21 00:00:00 | functional overlap between Phc2 and Phc1 along with a strict dose-dependent requirement during anterior-posterior (A-P) patterning | 16024804 |
| Type | IDs |
|---|---|
| Synonymous | A3galt2, AA415044, D130050K19Rik, D4Ertd810e, Edr2, Mph2, p36 |
| Gene |
UniProtKB-ID:
PHC2_MOUSE
UniprotKB:
Q9QWH1
UniParc:
UPI00000E6359,
UPI0000022FD4
EMBL:
BC071246,
AL611969,
AL611983,
AF060076,
BC057571,
AB062362,
U81491
Ensembl:
ENSMUSG00000028796
KO:
mmu:54383
|
| Nucleutide sequences |
EMBL-CDS:
BAB93527.1,
AAC23570.1,
AAD00519.1,
AAH57571.1,
AAH71246.1
Ensembl_TRS:
ENSMUST00000106080,
ENSMUST00000030588,
ENSMUST00000106079
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000030588,
ENSMUSP00000101689,
ENSMUSP00000101690
RefSeq:
XP_017175809.1,
XP_006503297.1,
NP_001182059.1,
NP_061244.1,
NP_001182012.1,
XP_006503299.1,
XP_006503301.1,
XP_011238878.1,
XP_036020134.1
|
| Others |
UniRef100:
UniRef100_Q9QWH1
UniRef90:
UniRef90_Q9QWH1
UniRef50:
UniRef50_Q8IXK0
UniGene:
Mm.473738,
Mm.490300
CCDS:
CCDS57297.1,
CCDS18674.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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