| Type | Description |
|---|---|
| Definition | FXYD domain containing ion transport regulator 5 |
| Date | Results | Publications |
|---|---|---|
| 2020-10-24 14:00:00 | A FXYD5/TGFbeta/SMAD positive feedback loop drives epithelialtomesenchymal transition and promotes tumor growth and metastasis in ovarian cancer. | 31746425 |
| 2020-05-23 10:58:00 | our study demonstrated that FXYD5 is an HGSOC-associated molecule, especially overexpressed in cases characterised by shorter survival, chemotherapy resistance and disease recurrence/progression, so it might be useful for identification of patients at higher risk of worse prognosis at the time of diagnosis. | 31434988 |
| 2017-08-05 10:08:00 | the ratio between FXYD5 and alpha1-beta1 heterodimer determines whether the Na,K-ATPase acts as a positive or negative regulator of intercellular adhesion. | 27142834 |
| 2016-12-17 10:53:00 | Knockdown of FXYD5 in MDA-MB-231 breast cancer cells largely decreases expression and secretion of the chemokine CCL2 (MCP-1). A related effect has also been observed in renal cell carcinoma cells. | 27006401 |
| 2016-09-24 10:51:00 | Study demonstrated that the expression of FXYD1, FXYD3 and FXYD5 is elevated in the lungs of Acute respiratory distress syndrome patients | 26410457 |
| Type | IDs |
|---|---|
| Synonymous | DYSAD, HSPC113, IWU1, KCT1, OIT2, PRO6241, RIC |
| Gene |
UniProtKB-ID:
FXYD5_HUMAN,
F5H4X8_HUMAN
UniprotKB:
Q96DB9,
F5H4X8
UniParc:
UPI000059D6E3,
UPI0000048F47,
UPI000206559C
EMBL:
AF177940,
AY358991,
AC020907,
AB072911,
BC009642,
BT007343,
AC002390,
AF161462
Ensembl:
ENSG00000089327
KO:
hsa:53827
|
| Nucleutide sequences |
EMBL-CDS:
AAH09642.1,
AAG09301.1,
AAP36007.1,
AAQ89350.1,
BAB83766.1,
AAF29077.1
Gene_ORFName:
HSPC113,
UNQ2561/PRO6241
Ensembl_TRS:
ENST00000392217,
ENST00000423817,
ENST00000342879,
ENST00000590686,
ENST00000392219,
ENST00000541435,
ENST00000543307,
ENST00000588699
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000344254,
ENSP00000376053,
ENSP00000443390,
ENSP00000376051,
ENSP00000393848,
ENSP00000465667,
ENSP00000467053,
ENSP00000444839
RefSeq:
NP_659003.1,
NP_054883.3,
NP_001158077.1,
NP_001307841.1,
NP_001307842.1
|
| Others |
UniRef100:
UniRef100_F5H4X8,
UniRef100_Q96DB9
UniRef90:
UniRef90_Q96DB9,
UniRef90_A0A2I3MW60
UniRef50:
UniRef50_Q96DB9
UniGene:
Hs.333418
CCDS:
CCDS12447.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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