| Type | Description |
|---|---|
| Definition | sodium voltage-gated channel alpha subunit 9 |
| Date | Results | Publications |
|---|---|---|
| 2014-08-16 10:41:00 | TNF-alpha up-regulates NaV1.7 mRNA in both adrenal chromaffin cells and dorsal root ganglia (DRG) neurons, highlighting the peripheral nociceptive mechanism of TNF-alpha | 24445633 |
| 2013-05-25 12:11:00 | Findings suggest that the endothelin-1-induced down-regulation of NaV1.7 (SCN9A) diminishes NaV1.7-related catecholamine secretion and dephosphorylation of tau. | 23434582 |
| 2010-10-23 11:13:00 | Nav1.7-Ca2+ influx-induced increased phosphorylations of extracellular signal-regulated kinase (ERK) and p38 attenuate tau phosphorylation via glycogen synthase kinase-3beta: priming of Nav1.7 gating by ERK and p38 | 20470771 |
| 2010-01-21 00:00:00 | Na influx via scn9a converged on inhibitory phosphorylation of glycogen synthase kinase-3beta, decreasing tau phosphorylation | 19428794 |
| 2010-01-21 00:00:00 | constitutively phosphorylated/activated ERK destabilizes Na(+) channel alpha-subunit mRNA via translational event, which negatively regulates steady-state level of alpha-subunit mRNA and cell surface expression of functional Na(+) channels. | 12695541 |
| Type | IDs |
|---|---|
| Gene | |
| Nucleutide sequences | |
| Protein sequencees |
RefSeq:
XP_005202510.2,
XP_024831398.1,
NP_001104257.3,
XP_024831397.1,
XP_024831395.1
|
| Others |
UniGene:
Bt.61065
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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