| Type | Description |
|---|---|
| Definition | paired like homeodomain 2 |
| Date | Results | Publications |
|---|---|---|
| 2021-03-06 13:25:00 | The diagnosis and phacoemulsification in combination with intraocular lens implantation for an Axenfeld-Rieger syndrome patient with small cornea: a case report. | 32295643 |
| 2020-10-31 13:20:00 | In Silico Assessment of Genetic Variation in PITX2 Reveals the Molecular Mechanisms of Calcium-Mediated Cellular Triggered Activity in Atrial Fibrillation(.) | 33018479 |
| 2020-06-06 13:19:00 | Findings suggest that downregulation of Pitx2c may regulate atrial fibrosis through modulating calcium homeostasis, which may contribute to its role in anti-atrial fibrosis, and Pitx2c downregulation may change the atrial electrophysiology and atrial fibrillation occurrence through modulating fibroblast activity. | 31378929 |
| 2020-02-08 11:53:00 | Heterologous PITX2 expression induced ABCB1, repressed hOCT3/SLC22A3, enhanced vincristine resistance and diminished proliferation inhibition in colonic and kidney tumor cells. | 30742940 |
| 2020-01-04 10:06:00 | High PITX2 expression was observed in non-functional pituitary neuroendocrine tumors with cavernous sinus invasion, suggesting that PITX2 may be involved in cavernous sinus invasion of pituitary neuroendocrine tumors | 30903445 |
| Type | IDs |
|---|---|
| Synonymous | ARP1, ASGD4, Brx1, IDG2, IGDS, IGDS2, IHG2, IRID2, Otlx2, PTX2, RGS, RIEG, RIEG1, RS |
| Gene |
UniProtKB-ID:
PITX2_HUMAN
UniprotKB:
Q99697
UniParc:
UPI0000131B4D,
UPI000002B123,
UPI000002B122
EMBL:
BC013998,
CH471057,
AF238048,
BC106010,
AF048722,
U69961,
AF048721,
AK291591,
AK127829,
AK313987,
AF048720
Ensembl:
ENSG00000164093
KO:
hsa:5308
|
| Nucleutide sequences |
EMBL-CDS:
BAG54582.1,
EAX06263.1,
BAG36699.1,
AAK15048.1,
EAX06264.1,
AAI06011.1,
AAC39716.1,
AAC16257.1,
EAX06262.1,
AAH13998.1,
AAC39717.1,
AAC39718.1,
BAF84280.1
Ensembl_TRS:
ENST00000354925,
ENST00000613094,
ENST00000355080,
ENST00000614423,
ENST00000644743,
ENST00000616641,
ENST00000394595
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000481951,
ENSP00000484909,
ENSP00000378095,
ENSP00000495061,
ENSP00000347192,
ENSP00000484763,
ENSP00000347004
RefSeq:
NP_001191328.1,
NP_001191326.1,
NP_700476.1,
NP_001191327.1,
NP_000316.2,
NP_700475.1,
XP_024309858.1
|
| Others |
UniRef100:
UniRef100_Q99697
UniRef90:
UniRef90_P97474
UniRef50:
UniRef50_P97474
UniGene:
Hs.643588,
Hs.738484
CCDS:
CCDS3694.1,
CCDS3692.1,
CCDS3693.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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