| Type | Description |
|---|---|
| Definition | protein geranylgeranyltransferase type I subunit beta |
| Date | Results | Publications |
|---|---|---|
| 2013-10-26 13:57:00 | our study showed, for the first time, that HIF-1alpha was regulated by protein prenylation transferase GGTI and mediated the effect of GGTI on glioma cell migration and invasion | 23475391 |
| 2012-03-31 11:48:00 | our findings identify Geranylgeranyl transferase 1 as a key regulator of human airway smooth muscle cell viability | 22160308 |
| 2010-11-27 10:46:00 | knockdown of GGTase-Ibeta inhibited invasion, disrupted F-actin organization and decreased the level of cofilin in PC-3 cells. | 20446922 |
| 2010-06-30 22:05:00 | Observational study of gene-disease association, gene-environment interaction, and pharmacogenomic / toxicogenomic. (HuGE Navigator) | 20403997 |
| 2010-01-21 00:00:00 | results suggest that geranylgeranylation of RhoA is critical for cancer cell invasion | 14598891 |
| Type | IDs |
|---|---|
| Synonymous | BGGI, GGTI |
| Gene |
UniProtKB-ID:
PGTB1_HUMAN
UniprotKB:
P53609
UniParc:
UPI0000D6166A,
UPI00001AEC1C
EMBL:
AC008494,
AY780790,
L25441
Ensembl:
ENSG00000164219
KO:
hsa:5229
|
| Nucleutide sequences |
EMBL-CDS:
AAV98360.1,
AAA35888.1
Ensembl_TRS:
ENST00000379615,
ENST00000419445
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000368935,
ENSP00000404676
RefSeq:
XP_011541794.1,
XP_011541792.1,
XP_005272077.2,
NP_005014.2
|
| Others |
UniRef100:
UniRef100_P53609
UniRef90:
UniRef90_P53609
UniRef50:
UniRef50_P53610
UniGene:
Hs.254006
CCDS:
CCDS4116.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
{{protein.nucleotideVersion}}
Ensembl: {{protein.nucleotideEnsembl}} |
{{protein.proteinVersion}}
Ensembl: {{protein.proteinEnsembl}} |
{{uniprot}} , |
Definition: {{{protein.definition}}}Transcript Veriant:{{protein.transcriptVeriant}} Status: {{protein.status}} |
||||
| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
||||
暂无数据
| Pubmed编号 | 文献信息 | 发表日期 | 相关基因 |
|---|---|---|---|
| 32694731 |
Nat Metab Michael Aregger , Keith A Lawson , Maximillian Billmann , Michael Costanzo , Amy H Y Tong , Katherine Chan , Mahfuzur Rahman , Kevin R Brown , Catherine Ross , Matej Usaj , Lucy Nedyalkova , Olga Sizova , Andrea Habsid , Judy Pawling , Zhen-Yuan Lin , Hala Abdouni , Cassandra J Wong , Alexander Weiss , Patricia Mero , James W Dennis , Anne-Claude Gingras , Chad L Myers , Brenda J Andrews , Charles Boone , Jason Moffat |
2020-06-01 | - |
| 32296183 |
A reference map of the human binary protein interactome. Nature Katja Luck , Dae-Kyum Kim , Luke Lambourne , Kerstin Spirohn , Bridget E Begg , Wenting Bian , Ruth Brignall , Tiziana Cafarelli , Francisco J Campos-Laborie , Benoit Charloteaux , Dongsic Choi , Atina G Coté , Meaghan Daley , Steven Deimling , Alice Desbuleux , Amélie Dricot , Marinella Gebbia , Madeleine F Hardy , Nishka Kishore , Jennifer J Knapp , István A Kovács , Irma Lemmens , Miles W Mee , Joseph C Mellor , Carl Pollis , Carles Pons , Aaron D Richardson , Sadie Schlabach , Bridget Teeking , Anupama Yadav , Mariana Babor , Dawit Balcha , Omer Basha , Christian Bowman-Colin , Suet-Feung Chin , Soon Gang Choi , Claudia Colabella , Georges Coppin , Cassandra D'Amata , David De Ridder , Steffi De Rouck , Miquel Duran-Frigola , Hanane Ennajdaoui , Florian Goebels , Liana Goehring , Anjali Gopal , Ghazal Haddad , Elodie Hatchi , Mohamed Helmy , Yves Jacob , Yoseph Kassa , Serena Landini , Roujia Li , Natascha van Lieshout , Andrew MacWilliams , Dylan Markey , Joseph N Paulson , Sudharshan Rangarajan , John Rasla , Ashyad Rayhan , Thomas Rolland , Adriana San-Miguel , Yun Shen , Dayag Sheykhkarimli , Gloria M Sheynkman , Eyal Simonovsky , Murat TaÅan , Alexander Tejeda , Vincent Tropepe , Jean-Claude Twizere , Yang Wang , Robert J Weatheritt , Jochen Weile , Yu Xia , Xinping Yang , Esti Yeger-Lotem , Quan Zhong , Patrick Aloy , Gary D Bader , Javier De Las Rivas , Suzanne Gaudet , Tong Hao , Janusz Rak , Jan Tavernier , David E Hill , Marc Vidal , Frederick P Roth , Michael A Calderwood |
2020-04-01 | - |
| 31980649 |
Nat Commun Susan A Kennedy , Mohamed-Ali Jarboui , Sriganesh Srihari , Cinzia Raso , Kenneth Bryan , Layal Dernayka , Theodosia Charitou , Manuel Bernal-Llinares , Carlos Herrera-Montavez , Aleksandar Krstic , David Matallanas , Max Kotlyar , Igor Jurisica , Jasna Curak , Victoria Wong , Igor Stagljar , Thierry LeBihan , Lisa Imrie , Priyanka Pillai , Miriam A Lynn , Erik Fasterius , Cristina Al-Khalili Szigyarto , James Breen , Christina Kiel , Luis Serrano , Nora Rauch , Oleksii Rukhlenko , Boris N Kholodenko , Luis F Iglesias-Martinez , Colm J Ryan , Ruth Pilkington , Patrizia Cammareri , Owen Sansom , Steven Shave , Manfred Auer , Nicola Horn , Franziska Klose , Marius Ueffing , Karsten Boldt , David J Lynn , Walter Kolch |
2020-01-24 | - |
| 28514442 |
Architecture of the human interactome defines protein communities and disease networks. Nature Edward L Huttlin , Raphael J Bruckner , Joao A Paulo , Joe R Cannon , Lily Ting , Kurt Baltier , Greg Colby , Fana Gebreab , Melanie P Gygi , Hannah Parzen , John Szpyt , Stanley Tam , Gabriela Zarraga , Laura Pontano-Vaites , Sharan Swarup , Anne E White , Devin K Schweppe , Ramin Rad , Brian K Erickson , Robert A Obar , K G Guruharsha , Kejie Li , Spyros Artavanis-Tsakonas , Steven P Gygi , J Wade Harper |
2017-05-25 | - |
| 26186194 |
The BioPlex Network: A Systematic Exploration of the Human Interactome. Cell Edward L Huttlin , Lily Ting , Raphael J Bruckner , Fana Gebreab , Melanie P Gygi , John Szpyt , Stanley Tam , Gabriela Zarraga , Greg Colby , Kurt Baltier , Rui Dong , Virginia Guarani , Laura Pontano Vaites , Alban Ordureau , Ramin Rad , Brian K Erickson , Martin Wühr , Joel Chick , Bo Zhai , Deepak Kolippakkam , Julian Mintseris , Robert A Obar , Tim Harris , Spyros Artavanis-Tsakonas , Mathew E Sowa , Pietro De Camilli , Joao A Paulo , J Wade Harper , Steven P Gygi |
2015-07-16 | - |
| 24981860 |
Cell Rep Edyta Marcon , Zuyao Ni , Shuye Pu , Andrei L Turinsky , Sandra Smiley Trimble , Jonathan B Olsen , Rosalind Silverman-Gavrila , Lorelei Silverman-Gavrila , Sadhna Phanse , Hongbo Guo , Guoqing Zhong , Xinghua Guo , Peter Young , Swneke Bailey , Denitza Roudeva , Dorothy Zhao , Johannes Hewel , Joyce Li , Susanne Gräslund , Marcin Paduch , Anthony A Kossiakoff , Mathieu Lupien , Andrew Emili , Shoshana J Wodak , Jack Greenblatt |
2014-07-10 | - |
| 23475391 |
Geranylgeranyltransferase I regulates HIF-1α promoting glioblastoma cell migration and invasion. J. Neurooncol. Xiuping Zhou , Zhi Liu , Qiong Shi , Jiantong Jiao , Wenbin Bian , Xu Song , Jianbing Mo , Ben Sang , Yinfu Xu , Jinming Qian , Yuewen Chao , Rutong Yu |
2013-05-01 | - |
| 22863883 |
A high-throughput approach for measuring temporal changes in the interactome. Nat. Methods Anders R Kristensen , Joerg Gsponer , Leonard J Foster |
2012-09-01 |
GNPDA1,
LOC100128588,
PDCD6IP,
PDCD6,
GNE,
TOM1L1,
TOM1,
RANBP9,
SMC4,
UBA2,
SAE1,
FARSB,
DNM1L,
ABCF2,
DPP3,
HUWE1,
COL4A3BP,
ARPC5,
ARPC4,
ARPC3,
ARPC1B,
ACTR3,
ACTR2,
NUBP2,
ARPC2,
ACTR1B,
ACTR1A,
PDIA6,
TRAP1,
OPTN,
NAMPT,
RBM12,
G3BP1,
ABI2,
TRIM28,
WASF2,
TXNDC9,
PRMT3,
PSME3,
DDX39A,
PSMD14,
PLIN3,
HNRNPR,
GPHN,
POP7,
CDK9,
STAM2,
STUB1,
UBE4B,
SF3A1,
CDKN2A,
MAEA,
RRAGB,
TFG,
NPM3,
TUBB3,
TUBB4A,
TUBB4B,
NDRG1,
MYL9,
RACK1,
BASP1,
YAP1,
PRMT5,
ARIH2,
ACAA2,
COG5,
PFDN6,
EIF3M,
SEC23B,
SEC23A,
CAP2,
CAP1,
CRTAP,
SYNCRIP,
VAT1,
CARM1,
DDX17,
HYOU1,
IPO7,
ATG7,
SSSCA1,
RNASEH2A,
GLRX3,
DCTN2,
ANP32B,
PRDX4,
ARPC1A,
RPP30,
RPP38,
ARFGEF2,
CCT7,
CCT4,
CCT2,
DRAP1,
SMC2,
AHSA1,
PAIP1,
PAICS
|
| 22632162 |
J Drug Target Chia-Wei Lin , Jung-hua Steven Kuo , Ming-shiou Jan |
2012-07-01 |
tat,
CDH2,
PFDN6,
PAICS,
SEPT9,
C1QTNF5,
TMEM37,
CTSZ,
C12orf50,
AP2B1,
DLST,
ESR1,
POFUT1,
ABL1,
SLC17A5,
HIC1,
HLA-G,
APAF1,
HSD11B2,
NDST1,
IFNAR2,
LIG3,
LIMK1,
MDFI,
PGGT1B,
CYCS,
RNF125,
PPP3R1,
ASH1L,
SYT13,
ZNF687,
MAGEE1,
GPR135,
SSR3,
KLF5,
TUB,
UBE2V1,
UPP1,
UPK3A,
CA5A,
SLC30A4,
EFCC1,
HKDC1,
APOL6,
MIXL1,
CASP8,
GARNL3,
CBX2,
CDK10,
TSPAN18,
SOCS3,
CRLF1,
H6PD
|
| 22160308 |
Geranylgeranyl transferase 1 modulates autophagy and apoptosis in human airway smooth muscle. Am J Physiol Lung Cell Mol Physiol Saeid Ghavami , Mark M Mutawe , Dedmer Schaafsma , Behzad Yeganeh , Helmut Unruh , Thomas Klonisch , Andrew J Halayko |
2012-02-15 | - |
| 排名 | 科研单位 | 文献 |
|---|---|---|
| {{affIndex+1}} |
{{aff.value}} |
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目前还没有研究热点单位
| 排名 | 研究人员 | 文献 |
|---|---|---|
| {{authorIndex+1}} |
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目前还没有研究热点人员