Type | Description |
---|---|
Definition | cytidine 5'-triphosphate synthase |
Date | Results | Publications |
---|---|---|
2013-11-30 11:20:00 | CTPS1 inhibition selectively blocks smooth muscle cell proliferation without disturbing or even promoting re-endothelialization for effective vascular repair after injury. | 24008161 |
2012-11-24 11:13:00 | Introduction of a fluorine atom at C3 of 3-deazauridine shifts its antimetabolic activity from inhibition of CTP synthetase to inhibition of orotidylate decarboxylase, an early event in the de novo pyrimidine nucleotide biosynthesis pathway. | 22730407 |
Type | IDs |
---|---|
Synonymous | Ctps1 |
Gene |
UniProtKB-ID:
PYRG1_MOUSE
UniprotKB:
P70698
UniParc:
UPI0000022F4F
EMBL:
BC006698,
AK148259,
U49350
Ensembl:
ENSMUSG00000028633
KO:
mmu:51797
|
Nucleutide sequences |
EMBL-CDS:
AAH06698.1,
AAB06942.1,
BAE28443.1
Ensembl_TRS:
ENSMUST00000030381
|
Protein sequencees |
Ensembl_PRO:
ENSMUSP00000030381
RefSeq:
NP_001342420.1,
NP_058028.2
|
Others |
UniRef100:
UniRef100_P70698
UniRef90:
UniRef90_P70698
UniRef50:
UniRef50_P70698
UniGene:
Mm.1815
CCDS:
CCDS18591.1
|
{{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
---|---|---|---|---|---|---|---|---|
Refseq |
{{protein.nucleotideVersion}}
Ensembl: {{protein.nucleotideEnsembl}} |
{{protein.proteinVersion}}
Ensembl: {{protein.proteinEnsembl}} |
{{uniprot}} , |
Definition: {{{protein.definition}}}Transcript Veriant:{{protein.transcriptVeriant}} Status: {{protein.status}} |
||||
Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
暂无数据
Pubmed编号 | 文献信息 | 发表日期 | 相关基因 |
---|---|---|---|
32325033 |
BraInMap Elucidates the Macromolecular Connectivity Landscape of Mammalian Brain. Cell Syst Reza Pourhaghighi , Peter E A Ash , Sadhna Phanse , Florian Goebels , Lucas Z M Hu , Siwei Chen , Yingying Zhang , Shayne D Wierbowski , Samantha Boudeau , Mohamed T Moutaoufik , Ramy H Malty , Edyta Malolepsza , Kalliopi Tsafou , Aparna Nathan , Graham Cromar , Hongbo Guo , Ali Al Abdullatif , Daniel J Apicco , Lindsay A Becker , Aaron D Gitler , Stefan M Pulst , Ahmed Youssef , Ryan Hekman , Pierre C Havugimana , Carl A White , Benjamin C Blum , Antonia Ratti , Camron D Bryant , John Parkinson , Kasper Lage , Mohan Babu , Haiyuan Yu , Gary D Bader , Benjamin Wolozin , Andrew Emili |
2020-04-22 | - |
30550785 |
Irisin Mediates Effects on Bone and Fat via αV Integrin Receptors. Cell Hyeonwoo Kim , Christiane D Wrann , Mark Jedrychowski , Sara Vidoni , Yukiko Kitase , Kenichi Nagano , Chenhe Zhou , Joshua Chou , Virginia-Jeni A Parkman , Scott J Novick , Timothy S Strutzenberg , Bruce D Pascal , Phuong T Le , Daniel J Brooks , Alexander M Roche , Kaitlyn K Gerber , Laura Mattheis , Wenjing Chen , Hua Tu , Mary L Bouxsein , Patrick R Griffin , Roland Baron , Clifford J Rosen , Lynda F Bonewald , Bruce M Spiegelman |
2018-12-13 | - |
30457570 |
Complementary proteomics strategies capture an ataxin-1 interactome in Neuro-2a cells. Sci Data Sunyuan Zhang , Nicholas A Williamson , Marie A Bogoyevitch |
2018-11-20 | - |
28378742 |
Fancd2 in vivo interaction network reveals a non-canonical role in mitochondrial function. Sci Rep Tingting Zhang , Wei Du , Andrew F Wilson , Satoshi H Namekawa , Paul R Andreassen , Amom Ruhikanta Meetei , Qishen Pang |
2017-04-05 | - |
26365490 |
Systematic identification of factors for provirus silencing in embryonic stem cells. Cell Bin Xia Yang , Chadi A El Farran , Hong Chao Guo , Tao Yu , Hai Tong Fang , Hao Fei Wang , Sharon Schlesinger , Yu Fen Samantha Seah , Germaine Yen Lin Goh , Suat Peng Neo , Yinghui Li , Matthew C Lorincz , Vinay Tergaonkar , Tit-Meng Lim , Lingyi Chen , Jayantha Gunaratne , James J Collins , Stephen P Goff , George Q Daley , Hu Li , Frederic A Bard , Yuin-Han Loh |
2015-09-24 |
Mdn1,
Wdr92,
Rtn1,
Rcor2,
Tsr1,
Ankrd28,
Chd4,
Dnajc9,
Cops8,
Rcc2,
Chaf1b,
Aldoc,
Mta1,
Mta3,
Brca1,
Ctnna1,
Cbx1,
Cbx3,
Cbx5,
Cdh1,
Eif3a,
Smarcad1,
Wdr5,
Ppm1g,
Trip12,
Hdac2,
Hspa8,
Hsph1,
Eif3e,
Lig1,
Mcm2,
Mcm4,
Mcm6,
Mre11a,
Msh2,
Msh6,
Ppp1r12a,
Npm1,
Npm3,
Pcna,
Ppp1ca,
Prpf8,
Rad50,
Ranbp2,
Rbbp4,
Rfc1,
Reps1,
Rfc2,
Ruvbl2,
Sec23a,
Cyfip1,
Sin3a,
Smarca4,
Smarcc1,
Eftud2,
Sde2,
Gps1,
Tbl1x,
Wdr18,
Sbno2,
Kat7,
Timeless,
Tjp2,
Sec24c,
Ulk1,
Usp9x,
Uxt,
Eif3l,
Prrc2c,
Ikbkap,
Nrd1,
Ipo7,
Gatad2a,
Heatr3,
Vac14,
Rbbp7,
Esrrb,
Cops3,
Cops5,
Cops4,
Cops6,
Aifm1,
Sec23b,
Chaf1a,
Trp53bp1,
Eif3b,
Hist1h3d,
Hist1h4d,
Snrnp200,
Hdac1,
Fbxo15,
Nckap1,
Ctps,
Rif1,
Ppp6r3,
Cdc23,
Eif3g,
Ddx20,
Eif3i
|
26370502 |
Prosaposin facilitates sortilin-independent lysosomal trafficking of progranulin. J. Cell Biol. Xiaolai Zhou , Lirong Sun , Francisco Bastos de Oliveira , Xiaoyang Qi , William J Brown , Marcus B Smolka , Ying Sun , Fenghua Hu |
2015-09-14 |
Grn,
Psap,
Sort1,
GRN,
PSAP,
SORT1
|
24457600 |
The central role of EED in the orchestration of polycomb group complexes. Nat Commun Qi Cao , Xiaoju Wang , Meng Zhao , Rendong Yang , Rohit Malik , Yuanyuan Qiao , Anton Poliakov , Anastasia K Yocum , Yong Li , Wei Chen , Xuhong Cao , Xia Jiang , Arun Dahiya , Clair Harris , Felix Y Feng , Sundeep Kalantry , Zhaohui S Qin , Saravana M Dhanasekaran , Arul M Chinnaiyan |
2014-01-01 | - |
24008161 |
CTP synthase 1, a smooth muscle-sensitive therapeutic target for effective vascular repair. Arterioscler. Thromb. Vasc. Biol. Rui Tang , Xiao-Bing Cui , Jia-Ning Wang , Shi-You Chen |
2013-10-01 |
Ctps,
Ctps1,
CTPS1
|
22922362 |
Transcription factor Foxp3 and its protein partners form a complex regulatory network. Nat. Immunol. Dipayan Rudra , Paul deRoos , Ashutosh Chaudhry , Rachel E Niec , Aaron Arvey , Robert M Samstein , Christina Leslie , Scott A Shaffer , David R Goodlett , Alexander Y Rudensky |
2012-10-01 |
Ldlrap1,
Kifc1,
Noc4l,
Acacb,
Papd4,
Rrp8,
Clk3,
Csnk1d,
Tsr1,
Utp15,
Nckap1l,
Lpxn,
Whsc1,
Chd4,
Bre,
Camk2d,
Foxp1,
Nusap1,
Sp110,
Rap1a,
Sec13,
Rps6ka3,
Cse1l,
Pwp2,
Lims1,
Add1,
Adsl,
Akp3,
Ap1b1,
Ap2a1,
Ap3s1,
Arpc1b,
Atm,
Bax,
Bcl7c,
Bop1,
Runx1,
Cbfb,
Cbx4,
Cct4,
Cd2ap,
Cdk11b,
Cdk6,
Cebpz,
Coro1a,
Coil,
Dbnl,
Dbt,
Dync1h1,
Dnm2,
Ddx19a,
Elf1,
Mark2,
Ercc3,
Igf2bp3,
Fasn,
Fen1,
Gata3,
Nr3c1,
Gspt1,
H1f0,
Hdac2,
Hdac3,
H2afx,
Hk2,
Hnrnpl,
Inpp5d,
Kif11,
Kif4,
Kpna3,
Lat,
Arhgef1,
Lig3,
Nup155,
Pfkfb3,
Max,
Mllt10,
Msh6,
Map4,
Myef2,
Nfatc2,
Ints6,
Zfp638,
Npm3,
Orc1,
Orc2,
Pcx,
Pdcd4,
Pdcd6ip,
Pfkl,
Plec,
Plk1,
Lcp1,
Pold1,
Nup88,
Prpf4b,
Psme3,
Slu7,
Qk
|
22730407 |
J Biol Chem Jan Balzarini , Federico Gago , Wim Kulik , André B P van Kuilenburg , Anna Karlsson , Matt A Peterson , Morris J Robins |
2012-08-31 | - |
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