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51795 Srpx

51795

Srpx

sushi-repeat-containing protein

protein-coding

Mus musculus

基因描述

Type Description
Definition sushi-repeat-containing protein

研究结论

Date Results Publications
2018-06-30 10:13:00 SRPX1 co-accumulated with Abeta deposits in cerebral blood vessels of all autopsied cases with severe cerebral amyloid angiopathy (CAA); no SRPX1 co-accumulated with Abeta deposits in senile plaques. Furthermore, we demonstrated that both Abeta40 and Abeta42 bound to SRPX1 in vitro and enhanced SRPX1 expression in primary cultures of cerebrovascular smooth muscle cells. SRPX1 enhanced caspase activity induced by Abeta40. 28478503
2016-05-28 12:33:00 drs regulates glucose metabolism via LDH-B. Downregulating drs may contribute to the Warburg effect, which is closely associated with malignant progression of cancer cells. 25620379
2012-01-21 10:19:00 Drs suppresses viral replication via mTOR-dependent pathway. 21983129
2010-01-21 00:00:00 Isolation of a novel variant of the tumor suppressor gene (mDRS-2) 12049817
2010-01-21 00:00:00 drs is involved in the maturation process of autophagy from autophagosomes to autolysosomes 19368996

名称对应

Type IDs
Synonymous DRS-1, DRS-2, drs, drs-1, drs-2
Gene
UniProtKB-ID: SRPX_MOUSE
UniprotKB: Q9R0M3
UniParc: UPI00000236DB, UPI0000025E2F
EMBL: BC022572, AB028050, BX005236, AK034696, AB028049
Ensembl: ENSMUSG00000090084
KO: mmu:51795
Nucleutide sequences
EMBL-CDS: BAA87328.1, BAA87329.1, BAC28800.1, AAH22572.1
Ensembl_TRS: ENSMUST00000115543, ENSMUST00000044789
Protein sequencees
Ensembl_PRO: ENSMUSP00000047926, ENSMUSP00000111205
RefSeq: NP_001352016.1, NP_058607.1
Others
UniRef100: UniRef100_Q9R0M3
UniRef90: UniRef90_P78539
UniRef50: UniRef50_P78539
UniGene: Mm.1927
CCDS: CCDS90696.1, CCDS30013.1

全选

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