| Type | Description |
|---|---|
| Definition | peroxisomal biogenesis factor 5 like |
| Date | Results | Publications |
|---|---|---|
| 2017-11-04 13:11:00 | allosteric coupling of the TRIP8b TPR domains both promotes binding to HCN channels and limits binding to type 1 peroxisomal targeting signal substrates. | 28887304 |
| 2017-11-04 12:38:00 | TRIP8b competes with a portion of the cAMP-binding site or distorts the binding site by making interactions with the binding pocket, thus acting predominantly as a competitive antagonist that inhibits the cyclic-nucleotide dependence of HCN channels. | 28864772 |
| 2015-05-09 12:38:00 | the sequential formation of a highly stable trimeric complex involving cargo protein, PEX7 and PEX5L stabilizes cargo binding and is a prerequisite for PTS2-mediated peroxisomal import. | 25538232 |
| 2015-05-02 12:15:00 | Data show that Rab8b-interacting protein TRIP8b does not compete with cyclic AMP for the same binding region of hyperpolarization activated cyclic nucleotide gated potassium channel 2 (HCN2). | 25197093 |
| 2014-06-21 10:09:00 | Nedd4-2 plays an important role in the regulation of HCN1 trafficking and may compete with TRIP8b(1a-4) in this process | 24451387 |
| Type | IDs |
|---|---|
| Synonymous | PEX5R, PEX5RP, PXR2, PXR2B, TRIP8b |
| Gene |
UniProtKB-ID:
PEX5R_HUMAN
UniprotKB:
Q8IYB4
UniParc:
UPI000006FAAB,
UPI0001B79774,
UPI0000EE2359,
UPI000036781C,
UPI0001B79776,
UPI0001B79777,
UPI0000049CE2,
UPI0001B79775
EMBL:
AC007687,
AK295349,
AK295386,
CH471052,
AC090024,
AK303716,
AJ245503,
AC092939,
AK299633,
AK294501,
AB032593,
AB032592,
BC036183
Ensembl:
ENSG00000114757
KO:
hsa:51555
|
| Nucleutide sequences |
EMBL-CDS:
CAC01120.1,
EAW78382.1,
BAH12054.1,
AAH36183.2,
BAH14028.1,
BAA92879.1,
BAA92878.1,
BAH13081.1,
BAH12041.1,
BAH11791.1
Ensembl_TRS:
ENST00000465751,
ENST00000468741,
ENST00000392649,
ENST00000467460,
ENST00000476138,
ENST00000263962,
ENST00000485199,
ENST00000472994,
ENST00000464614
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000376420,
ENSP00000419348,
ENSP00000420555,
ENSP00000418440,
ENSP00000418665,
ENSP00000418054,
ENSP00000263962,
ENSP00000419975,
ENSP00000417270
RefSeq:
NP_001243682.1,
NP_001243680.1,
NP_001336321.1,
NP_001243684.1,
NP_001243685.1,
NP_001336338.1,
XP_011511193.1,
NP_001336323.1,
XP_011511190.1,
NP_001336328.1,
NP_001336339.1,
XP_024309359.1,
NP_057643.1,
NP_001336337.1,
NP_001336335.1,
XP_024309358.1,
XP_016862097.1,
NP_001336320.1,
NP_001243679.1,
NP_001336330.1,
NP_001243683.1,
XP_024309360.1,
NP_001336327.1,
XP_024309361.1,
NP_001336315.1,
NP_001336318.1,
NP_001336325.1,
NP_001336326.1,
NP_001336317.1,
XP_016862096.1,
NP_001243681.1,
NP_001336316.1,
NP_001336324.1,
NP_001336322.1,
XP_011511194.1,
NP_001336333.1,
NP_001336319.1
|
| Others |
UniRef100:
UniRef100_Q8IYB4
UniRef90:
UniRef90_Q925N3
UniRef50:
UniRef50_Q925N3
UniGene:
Hs.235331
CCDS:
CCDS58864.1,
CCDS3236.1,
CCDS58867.1,
CCDS58861.1,
CCDS58866.1,
CCDS58863.1,
CCDS58865.1,
CCDS58862.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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