| Type | Description |
|---|---|
| Definition | DNA polymerase kappa |
| Date | Results | Publications |
|---|---|---|
| 2021-04-03 13:36:00 | Translesion synthesis of 6-nitrochrysene-derived 2'-deoxyadenosine adduct in human cells. | 32721818 |
| 2020-10-03 12:57:00 | Kinetic Investigation of Translesion Synthesis across a 3-Nitrobenzanthrone-Derived DNA Lesion Catalyzed by Human Kappa. | 31286773 |
| 2020-09-26 13:02:00 | The polymorphisms (rs3213801 and rs5744533) of DNA polymerase kappa gene are not related with glioma risk and prognosis: A case-control study. | 31595696 |
| 2020-01-11 10:48:00 | pol kappa has roles both in maintaining and compromising genomic integrity. The expression of pol kappa is altered in several different cancer types, which can lead to genome instability. In addition, many cancer-associated single-nucleotide polymorphisms have been reported in the POLK gene, some of which are associated with poor survival and altered chemotherapy response | 31374881 |
| 2019-07-06 13:03:00 | observations from molecular dynamics simulations suggest a possible explanation for the observed experimental results that pol kappa adopts specific active and inactive conformations that depend on both the protein variant and the identity of the DNA adduct | 30004685 |
| Type | IDs |
|---|---|
| Synonymous | DINB1, DINP, POLQ |
| Gene |
UniProtKB-ID:
POLK_HUMAN,
A0A024RAP4_HUMAN
UniprotKB:
Q9UBT6,
A0A024RAP4
UniParc:
UPI0000497E04,
UPI0000073EF6,
UPI0000497E05,
UPI0000497E03,
UPI0000190820,
UPI0000497E06,
UPI000004D289,
UPI00004C8013
EMBL:
BC014955,
AB027564,
AF194973,
BC050718,
AC026424,
AC116341,
AC010245,
AF318313,
AK091659,
AB036934,
CH471084,
AY769931,
AF315602,
AY769929,
AK314610,
AY273797,
AF163570,
AB036935,
AY769930,
AY769932
Ensembl:
ENSG00000122008
KO:
hsa:51426
|
| Nucleutide sequences |
EMBL-CDS:
AAN15781.1,
AAF23270.1,
AAV80828.1,
AAV80829.1,
BAA86943.1,
AAP12648.1,
BAB58976.1,
AAV80827.1,
BAC03714.1,
AAH50718.1,
EAW95763.1,
AAH14955.1,
BAG37179.1,
AAV80830.1,
AAN15780.1,
BAB58975.1,
AAF02540.1,
EAW95764.1,
EAW95765.1
Gene_ORFName:
hCG_18353
Ensembl_TRS:
ENST00000508526,
ENST00000510815,
ENST00000241436,
ENST00000515295,
ENST00000504026,
ENST00000509126
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000425075,
ENSP00000426853,
ENSP00000424174,
ENSP00000241436,
ENSP00000422094,
ENSP00000423532
RefSeq:
NP_001374040.1,
NP_057302.1,
NP_001332850.1,
NP_001374039.1,
NP_001332851.1,
NP_001374042.1,
NP_001374041.1
|
| Others |
UniRef100:
UniRef100_Q9UBT6
UniRef90:
UniRef90_Q9UBT6
UniRef50:
UniRef50_Q9UBT6
UniGene:
Hs.135756
CCDS:
CCDS4030.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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