Human Y-Family DNA Polymerase Îº Is More Tolerant to Changes in Its Active Site Loop than Its Ortholog Escherichia coli DinB.

Chem. Res. Toxicol.2017 Nov 20;30(11):2002-2012. doi:10.1021/acs.chemrestox.7b00175. Epub 2017 Sep 06

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-furfuryl-dG adduct and dCTP, which correlates with activity. Overall we find that pol Îº is more tolerant to changes in the active site loop than DinB.

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Human Y-Family DNA Polymerase Îº Is More Tolerant to Changes in Its Active Site Loop than Its Ortholog Escherichia coli DinB.

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