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51194 IPO11

51194

IPO11

importin 11

protein-coding

Homo sapiens

基因描述

Type Description
Definition importin 11

研究结论

Date Results Publications
2020-09-19 16:30:00 IPO11 mediates betacatenin nuclear import in a subset of colorectal cancers. 31881079
2018-11-10 12:01:00 High IPO11 expression is associated with migration, invasion, and progression of bladder cancer. 29602637
2018-03-03 11:47:00 IPO11 copy number amplification and importin-11 overexpression are promising biomarkers for predicting the progression and poor prognosis of patients with NMIBC. 27689332
2017-11-25 15:57:00 IPO11 provides protection in another way, the researchers found. The transport receptor also shuttles UBE2E1, an enzyme necessary for PTEN ubiquitination, into the nucleus. Thanks to IPO11, normal cells keep all of their UBE2E1 in the nucleus, allowing PTEN to continue functioning in the cytoplasm. In cells lacking IPO11, UBE2E1 remains in the cytoplasm and promotes the destruction of PTEN. 28258103
2016-07-30 11:16:00 IPO11-HTR1A is a significant risk gene region for attention deficit hyperactivity disorder in Caucasians. 26079129

名称对应

Type IDs
Synonymous RanBP11
Gene
UniProtKB-ID: IPO11_HUMAN
UniprotKB: Q9UI26
UniParc: UPI00000737DF, UPI00017EE9F4
EMBL: CH471137, AK302781, AK001696, AF111109, BC033776, AC008859, AL162083, BC031694
Ensembl: ENSG00000086200
KO: hsa:51194
Nucleutide sequences
EMBL-CDS: BAA91843.1, AAH31694.1, AAF21936.1, AAH33776.1, EAW51379.1, EAW51380.1, BAG63985.1, CAB82416.1
Ensembl_TRS: ENST00000325324, ENST00000409296
Protein sequencees
Ensembl_PRO: ENSP00000386992, ENSP00000316651
RefSeq: NP_001128251.1, NP_057422.3
Others
UniRef100: UniRef100_Q9UI26
UniRef90: UniRef90_Q9UI26
UniRef50: UniRef50_Q9UI26
UniGene: Hs.482269
CCDS: CCDS47217.1, CCDS34167.1

全选

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研究热度

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