| Type | Description |
|---|---|
| Definition | immediate early response 3 interacting protein 1 |
| Date | Results | Publications |
|---|---|---|
| 2021-01-23 13:03:00 | A human tissue screen identifies a regulator of ER secretion as a brain-size determinant. | 33122427 |
| 2017-12-09 11:28:00 | 233 T > C mutation in the IER3IP1 causes microcephaly with simplified gyral pattern, epilepsy and permanent neonatal diabetes syndrome. | 28711742 |
| 2013-06-22 11:51:00 | We expand the phenotypic spectrum of MEDS caused by IER3IP1 gene mutations and propose that WRS and MEDS are overlapping clinical syndromes, displaying significant gene-dependent clinical variability. | 22991235 |
| 2011-06-18 10:51:00 | Inhibiting the expression of IER3IP1 can inhibit erythroid differentiation and elevate the proliferation of K562 cells. | 19951536 |
| 2010-03-22 11:17:00 | IER3IP1 gene expression is regulated by Sp1, Sp3, and the TNF-a; induction of the gene in HepG2 liver cancer cell line | 19885854 |
| Type | IDs |
|---|---|
| Synonymous | HSPC039, MEDS, PRO2309 |
| Gene |
UniProtKB-ID:
IR3IP_HUMAN
UniprotKB:
Q9Y5U9
UniParc:
UPI000007015F
EMBL:
AF371963,
BC017391,
CR533488,
AL136667,
AF125100,
AF164798,
BC010888
Ensembl:
ENSG00000134049
KO:
hsa:51124
|
| Nucleutide sequences |
EMBL-CDS:
AAF80762.1,
AAD39917.1,
AAK53816.1,
CAB66602.1,
AAH10888.1,
CAG38519.1,
AAH17391.1
Gene_ORFName:
HSPC039
Ensembl_TRS:
ENST00000256433
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000256433
RefSeq:
NP_057181.1
|
| Others |
UniRef100:
UniRef100_Q9Y5U9
UniRef90:
UniRef90_Q9Y5U9
UniRef50:
UniRef50_Q9Y5U9
UniGene:
Hs.130917
CCDS:
CCDS11933.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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