| Type | Description |
|---|---|
| Definition | lactamase beta 2 |
| Date | Results | Publications |
|---|---|---|
| 2017-09-30 13:50:00 | This genome-wide study of never smokers from the general population identified two independent regions related to erythrocyte cadmium. The strongest locus covers the XKR9 and LACTB2 genes, which both could have related functions in cadmium absorption and metabolism | 27005419 |
| 2016-07-30 11:27:00 | this study discovered that LACTB2 is an endoribonuclease that is involved in the turnover of mitochondrial RNA, and is essential for mitochondrial function in human cells. | 26826708 |
| 2016-05-28 11:55:00 | Disruption of NCOA2 by recurrent fusion with LACTB2 in colorectal cancer | 25823027 |
| 2010-12-05 22:08:00 | Observational study of gene-disease association. (HuGE Navigator) | 20877624 |
| Type | IDs |
|---|---|
| Synonymous | CGI-83 |
| Gene |
UniProtKB-ID:
LACB2_HUMAN,
A0A024R811_HUMAN
UniprotKB:
Q53H82,
A0A024R811
UniParc:
UPI00000382DA
EMBL:
AF151841,
CH471068,
AK222699,
BC000878,
HM005563,
AK290201
Ensembl:
ENSG00000147592
KO:
hsa:51110
|
| Nucleutide sequences |
EMBL-CDS:
AAD34078.1,
BAD96419.1,
EAW86969.1,
AAH00878.1,
BAF82890.1,
AEE61160.1,
EAW86970.1
Gene_ORFName:
CGI-83,
hCG_18450
Ensembl_TRS:
ENST00000522447,
ENST00000276590
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000428801,
ENSP00000276590
RefSeq:
NP_057111.1
|
| Others |
UniRef100:
UniRef100_Q53H82
UniRef90:
UniRef90_Q53H82
UniRef50:
UniRef50_Q53H82
UniGene:
Hs.118554
CCDS:
CCDS6208.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
{{protein.nucleotideVersion}}
Ensembl: {{protein.nucleotideEnsembl}} |
{{protein.proteinVersion}}
Ensembl: {{protein.proteinEnsembl}} |
{{uniprot}} , |
Definition: {{{protein.definition}}}Transcript Veriant:{{protein.transcriptVeriant}} Status: {{protein.status}} |
||||
| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
||||
暂无数据
| Pubmed编号 | 文献信息 | 发表日期 | 相关基因 |
|---|---|---|---|
| 31536960 |
iScience Mohamed Taha Moutaoufik , Ramy Malty , Shahreen Amin , Qingzhou Zhang , Sadhna Phanse , Alla Gagarinova , Mara Zilocchi , Larissa Hoell , Zoran Minic , Maria Gagarinova , Hiroyuki Aoki , Jocelyn Stockwell , Matthew Jessulat , Florian Goebels , Kirsten Broderick , Nichollas E Scott , James Vlasblom , Gabriel Musso , Bhanu Prasad , Eleonora Lamantea , Barbara Garavaglia , Alex Rajput , Kei Murayama , Yasushi Okazaki , Leonard J Foster , Gary D Bader , Francisco S Cayabyab , Mohan Babu |
2019-09-27 | - |
| 28514442 |
Architecture of the human interactome defines protein communities and disease networks. Nature Edward L Huttlin , Raphael J Bruckner , Joao A Paulo , Joe R Cannon , Lily Ting , Kurt Baltier , Greg Colby , Fana Gebreab , Melanie P Gygi , Hannah Parzen , John Szpyt , Stanley Tam , Gabriela Zarraga , Laura Pontano-Vaites , Sharan Swarup , Anne E White , Devin K Schweppe , Ramin Rad , Brian K Erickson , Robert A Obar , K G Guruharsha , Kejie Li , Spyros Artavanis-Tsakonas , Steven P Gygi , J Wade Harper |
2017-05-25 | - |
| 27005419 |
Hum. Mol. Genet. Yan Borné , Martin Söderholm , Lars Barregard , Björn Fagerberg , Margaretha Persson , Olle Melander , Frank Thévenod , Bo Hedblad , Gunnar Engström |
2016-06-01 | - |
| 26826708 |
Identification of LACTB2, a metallo-β-lactamase protein, as a human mitochondrial endoribonuclease. Nucleic Acids Res. Shiri Levy , Charles K Allerston , Varda Liveanu , Mouna R Habib , Opher Gileadi , Gadi Schuster |
2016-02-29 | - |
| 25823027 |
Disruption of NCOA2 by recurrent fusion with LACTB2 in colorectal cancer. Oncogene J Yu , W K K Wu , Q Liang , N Zhang , J He , X Li , X Zhang , L Xu , M T V Chan , S S M Ng , J J Y Sung |
2016-01-14 | - |
| 26344197 |
Panorama of ancient metazoan macromolecular complexes. Nature Cuihong Wan , Blake Borgeson , Sadhna Phanse , Fan Tu , Kevin Drew , Greg Clark , Xuejian Xiong , Olga Kagan , Julian Kwan , Alexandr Bezginov , Kyle Chessman , Swati Pal , Graham Cromar , Ophelia Papoulas , Zuyao Ni , Daniel R Boutz , Snejana Stoilova , Pierre C Havugimana , Xinghua Guo , Ramy H Malty , Mihail Sarov , Jack Greenblatt , Mohan Babu , W Brent Derry , Elisabeth R Tillier , John B Wallingford , John Parkinson , Edward M Marcotte , Andrew Emili |
2015-09-17 |
AKT3,
MED6,
ABI1,
GNPDA1,
SRA1,
TDRD15,
HMGN1P30,
PDCD6IP,
PDCD6,
MED16,
ADA,
CHAF1A,
TOM1,
RANBP9,
SMC4,
ARPC4-TTLL3,
RBM14-RBM4,
RNF103-CHMP3,
CHURC1-FNTB,
AP1M2,
ISY1-RAB43,
UBA2,
SAE1,
FARSB,
DNM1L,
ABCF2,
COX17,
SCAMP2,
SCAMP3,
DPP3,
SNUPN,
HUWE1,
TSSC4,
ATP9A,
PQBP1,
COL4A3BP,
PTGES3L-AARSD1,
ARPC5,
ARPC4,
ARPC3,
ARPC1B,
ACTR3,
ACTR2,
NUBP2,
PPIF,
LOC101060521,
ARPC2,
RAD50,
ACTR1B,
ACTR1A,
ADAM8,
LRPPRC,
PDIA6,
TRAP1,
BCAP31,
NAMPT,
RBM12,
G3BP1,
ABI2,
CEBPZ,
TRIM28,
AASS,
ATP6AP2,
WASF2,
SLC25A13,
CDK2,
RBM7,
ALYREF,
TXNDC9,
LOC101929876,
PSME3,
MPHOSPH10,
MPHOSPH6,
CDK5,
NUTF2,
EIF1,
DDX39A,
PSMD14,
CDK7,
PLIN3,
HNRNPR,
MRPS31,
CDK8,
RABEPK,
RIDA,
SRRM1,
CDK9,
STAM2,
SF3B4,
ZMPSTE24,
AKAP8,
STUB1,
STAG1,
UBE4B,
PRSS16,
SIGMAR1,
BET1,
CWC27,
SAP18
|
| 26186194 |
The BioPlex Network: A Systematic Exploration of the Human Interactome. Cell Edward L Huttlin , Lily Ting , Raphael J Bruckner , Fana Gebreab , Melanie P Gygi , John Szpyt , Stanley Tam , Gabriela Zarraga , Greg Colby , Kurt Baltier , Rui Dong , Virginia Guarani , Laura Pontano Vaites , Alban Ordureau , Ramin Rad , Brian K Erickson , Martin Wühr , Joel Chick , Bo Zhai , Deepak Kolippakkam , Julian Mintseris , Robert A Obar , Tim Harris , Spyros Artavanis-Tsakonas , Mathew E Sowa , Pietro De Camilli , Joao A Paulo , J Wade Harper , Steven P Gygi |
2015-07-16 | - |
| 25416956 |
A proteome-scale map of the human interactome network. Cell Thomas Rolland , Murat TaÅan , Benoit Charloteaux , Samuel J Pevzner , Quan Zhong , Nidhi Sahni , Song Yi , Irma Lemmens , Celia Fontanillo , Roberto Mosca , Atanas Kamburov , Susan D Ghiassian , Xinping Yang , Lila Ghamsari , Dawit Balcha , Bridget E Begg , Pascal Braun , Marc Brehme , Martin P Broly , Anne-Ruxandra Carvunis , Dan Convery-Zupan , Roser Corominas , Jasmin Coulombe-Huntington , Elizabeth Dann , Matija Dreze , Amélie Dricot , Changyu Fan , Eric Franzosa , Fana Gebreab , Bryan J Gutierrez , Madeleine F Hardy , Mike Jin , Shuli Kang , Ruth Kiros , Guan Ning Lin , Katja Luck , Andrew MacWilliams , Jörg Menche , Ryan R Murray , Alexandre Palagi , Matthew M Poulin , Xavier Rambout , John Rasla , Patrick Reichert , Viviana Romero , Elien Ruyssinck , Julie M Sahalie , Annemarie Scholz , Akash A Shah , Amitabh Sharma , Yun Shen , Kerstin Spirohn , Stanley Tam , Alexander O Tejeda , Shelly A Trigg , Jean-Claude Twizere , Kerwin Vega , Jennifer Walsh , Michael E Cusick , Yu Xia , Albert-László Barabási , Lilia M Iakoucheva , Patrick Aloy , Javier De Las Rivas , Jan Tavernier , Michael A Calderwood , David E Hill , Tong Hao , Frederick P Roth , Marc Vidal |
2014-11-20 | - |
| 22939629 |
A census of human soluble protein complexes. Cell Pierre C Havugimana , G Traver Hart , Tamás Nepusz , Haixuan Yang , Andrei L Turinsky , Zhihua Li , Peggy I Wang , Daniel R Boutz , Vincent Fong , Sadhna Phanse , Mohan Babu , Stephanie A Craig , Pingzhao Hu , Cuihong Wan , James Vlasblom , Vaqaar-un-Nisa Dar , Alexandr Bezginov , Gregory W Clark , Gabriel C Wu , Shoshana J Wodak , Elisabeth R M Tillier , Alberto Paccanaro , Edward M Marcotte , Andrew Emili |
2012-08-31 |
SRB2,
TRA1,
MED6,
CDH2,
DDTL,
ABI1,
SRA1,
UQCRFS1P1,
SNRPGP15,
ZNF316,
LOC100132057,
PDCD6IP,
PDCD6,
MED16,
PIGK,
WASH1,
CHAF1A,
TOM1L1,
HMGXB4,
RANBP9,
SMC4,
UBA2,
SAE1,
FARSB,
ABCB6,
ABCF2,
TIMM23B,
SCAMP3,
DPP3,
HUWE1,
TSSC4,
PDCD7,
USH1C,
PQBP1,
ARPC5,
ARPC4,
ARPC3,
ARPC1B,
ACTR3,
ACTR2,
NUBP2,
TSFM,
PPIF,
ARPC2,
RAD50,
PREB,
ACTR1B,
ACTR1A,
RASGRP1,
LRPPRC,
PDIA6,
TRAP1,
RBM12,
G3BP1,
SUGP2,
TRIM28,
WASF2,
SLC25A13,
SORBS3,
ALYREF,
TXNDC9,
CDK4,
PRMT3,
PSME3,
MPHOSPH6,
CDK5,
NUTF2,
EIF1,
FLOT1,
PSMD14,
CDK7,
ADAM10,
PLIN3,
STX6,
MSLN,
HNRNPR,
MRPS31,
TIMM17B,
RIDA,
POP7,
SRRM1,
CDK9,
STAM2,
SF3B4,
ZMPSTE24,
STUB1,
UBE4B,
BET1,
CWC27,
SAP18,
SMNDC1,
BCAS2,
EIF1B,
SF3A1,
MAEA,
KATNB1,
TCIRG1,
RTN3,
LANCL1
|
| 21988832 |
Toward an understanding of the protein interaction network of the human liver. Mol. Syst. Biol. Jian Wang , Keke Huo , Lixin Ma , Liujun Tang , Dong Li , Xiaobi Huang , Yanzhi Yuan , Chunhua Li , Wei Wang , Wei Guan , Hui Chen , Chaozhi Jin , Juncheng Wei , Wanqiao Zhang , Yongsheng Yang , Qiongming Liu , Ying Zhou , Cuili Zhang , Zhihao Wu , Wangxiang Xu , Ying Zhang , Tao Liu , Donghui Yu , Yaping Zhang , Liang Chen , Dewu Zhu , Xing Zhong , Lixin Kang , Xiang Gan , Xiaolan Yu , Qi Ma , Jing Yan , Li Zhou , Zhongyang Liu , Yunping Zhu , Tao Zhou , Fuchu He , Xiaoming Yang |
2011-10-11 | - |
| 排名 | 科研单位 | 文献 |
|---|---|---|
| {{affIndex+1}} |
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目前还没有研究热点单位
| 排名 | 研究人员 | 文献 |
|---|---|---|
| {{authorIndex+1}} |
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目前还没有研究热点人员