| Type | Description |
|---|---|
| Definition | membrane associated guanylate kinase, WW and PDZ domain containing 2 |
| Date | Results | Publications |
|---|---|---|
| 2017-10-07 12:29:00 | In summary,MAGI-2 and Fyn protect dendrin fromNedd4-2-mediated ubiquitination and from nuclear translocation, thereby maintaining the physiologic homeostasis of podocytes, and the lack of MAGI-2 in podocytes results in FSGS. | 28539383 |
| 2016-05-28 11:30:00 | Magi2 is an essential component of the slit diaphragm complex that is required for nephrin localization and foot process formation. | 25993318 |
| 2016-05-07 11:20:00 | MAGI-2 has a critical role in maintaining the functional structure of the slit diaphragm and this molecule has an essential role in the functioning of the kidney filtration barrier. | 25108225 |
| 2015-07-04 16:02:00 | We showed the expression patterns of MAGI-2 in detail in adult mice. Significant Venus expression was detected in various regions of the brain, also detected in glomeruli of the kidney. We found the novel expression of MAGI-2 in the testis. | 22361463 |
| 2015-05-02 10:17:00 | MAGI-2 is required for the integrity of the kidney filter and podocyte survival. | 25271328 |
| Type | IDs |
|---|---|
| Synonymous | AIP-1, Acvri1, Acvrinp1, Acvrip1, Magi-2, S-SCAM, mKIAA0705 |
| Gene |
UniProtKB-ID:
MAGI2_MOUSE,
A0A0G2JEG6_MOUSE,
A0A0G2JE00_MOUSE
UniprotKB:
Q9WVQ1,
A0A0G2JEG6,
A0A0G2JE00
UniParc:
UPI0000D6615B,
UPI00000290E8,
UPI00005AC67D,
UPI0003D70B5D,
UPI00001D6A12,
UPI00000E9660
EMBL:
FO082287,
AC122347,
AC116329,
AK039336,
AC161802,
AC158590,
BC059005,
AC162892,
AB029485,
AC121774,
AC119269,
AK147530,
AC113596
Ensembl:
ENSMUSG00000040003
KO:
mmu:50791
|
| Nucleutide sequences |
EMBL-CDS:
AAH59005.1,
BAA82294.1,
BAE27976.1,
BAC30321.1
Ensembl_TRS:
ENSMUST00000088516,
ENSMUST00000115267,
ENSMUST00000101558,
ENSMUST00000197553,
ENSMUST00000197443,
ENSMUST00000197354
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000099094,
ENSMUSP00000110922,
ENSMUSP00000146769,
ENSMUSP00000085872,
ENSMUSP00000142764,
ENSMUSP00000142576
RefSeq:
XP_030110517.1,
XP_006535806.1,
NP_001164216.1,
XP_006535812.1,
XP_036021155.1,
XP_006535815.1,
XP_006535810.1,
XP_030110516.1,
XP_006535807.1,
XP_006535811.1,
NP_001164217.1,
NP_056638.1,
XP_006535808.1,
XP_006535813.1,
XP_006535814.1,
XP_036021154.1,
XP_017176457.1
|
| Others |
UniRef100:
UniRef100_A0A0G2JE00,
UniRef100_A0A0G2JEG6,
UniRef100_Q9WVQ1
UniRef90:
UniRef90_Q9WVQ1,
UniRef90_A0A0G2JEG6,
UniRef90_A0A0G2JE00
UniRef50:
UniRef50_Q86UL8,
UniRef50_Q9WVQ1
UniGene:
Mm.332231,
Mm.441283
CCDS:
CCDS39019.1,
CCDS51424.1,
CCDS51425.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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