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504186 Chrna10

504186

Chrna10

cholinergic receptor, nicotinic, alpha polypeptide 10

protein-coding

Mus musculus

基因描述

Type Description
Definition cholinergic receptor, nicotinic, alpha polypeptide 10

研究结论

Date Results Publications
2020-09-26 13:06:00 Attenuation in Nicotinic Acetylcholine Receptor alpha9 and alpha10 Subunit Double Knock-Out Mice of Experimental Autoimmune Encephalomyelitis. 31817275
2018-04-14 10:26:00 we developed RgIA4, a peptide that exhibits high potency for both human and rodent a9a10 nAChRs, and was at least 1,000-fold more selective for a9a10 nAChRs vs. all other molecular targets tested, including opioid and GABAB receptors 28223528
2010-01-21 00:00:00 Results demonstrate that alpha9(-/-) and alpha10(-/-) mice have overlapping but nonidentical phenotypes. 18077337
2010-01-21 00:00:00 Multiple features of the efferent postsynaptic complex to inner hair cells, in addition to the alpha9alpha10 nicotinic cholinergic receptors, are down-regulated in synchrony after the onset of hearing, leading to lack of responses to acetylcholine. 19452222
2008-07-30 10:20:00 Co-expression of the alpha10 subunit converts the normally weak acetylcholine-mediated activity of alpha9 to a more robustly active channel with identical physiological characteristics of the native mammalian outer hair cell cholinergic receptor. 11248107

名称对应

Type IDs
Gene
UniProtKB-ID: B2RX82_MOUSE
UniprotKB: B2RX82
UniParc: UPI0000193EB3
EMBL: BC151033, BC151035, BC147246, AC118592, BC147245, AC132297
Ensembl: ENSMUSG00000066279
KO: mmu:504186
Nucleutide sequences
EMBL-CDS: AAI51036.1, AAI47247.1, AAI51034.1, AAI47246.1
Ensembl_TRS: ENSMUST00000084830
Protein sequencees
Ensembl_PRO: ENSMUSP00000081891
RefSeq: XP_006508071.1, NP_001074893.1, XP_006508072.1
Others
UniRef100: UniRef100_B2RX82
UniRef90: UniRef90_Q9JLB5
UniRef50: UniRef50_Q9JLB5
UniGene: Mm.334074

全选

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