| Type | Description |
|---|---|
| Definition | serum response factor |
| Date | Results | Publications |
|---|---|---|
| 2020-10-03 12:53:00 | Crucial role of serum response factor in renal tubular epithelial cell epithelial-mesenchymal transition in hyperuricemic nephropathy. | 31774735 |
| 2020-09-26 13:04:00 | Changes in snail and SRF expression in the kidneys of diabetic rats during ageing. | 31668740 |
| 2018-11-10 11:20:00 | Results show decreased SRF levels in the substantia nigra (SN) of rotenone-treated rats that was associated with the loss of tyrosine hydroxylase (TH)-positive neurons. SRF expression was also reduced in rotenone-treated PC12 cells in vitro. In addition, Srf knockdown augmented rotenone-induced toxicity in PC12 cells. In contrast, overexpression of Srf attenuated the cells' sensitivity to rotenone. | 29196028 |
| 2018-10-20 10:46:00 | Findings suggested that hypoxia induced SRF upregulation in hypoxic pulmonary hypertension (HPH) rat model. CTGF mediated hypoxia-induced regulation of miR-26b and SRF in proliferation of pulmonary arterial smooth muscle cells. | 28816418 |
| 2018-02-03 11:45:00 | Increased SRF activity promotes EMT in TECs and dysfunction in DN. | 27260841 |
| Type | IDs |
|---|---|
| Synonymous | RGD1559787 |
| Gene |
UniProtKB-ID:
D3ZHH8_RAT
UniprotKB:
D3ZHH8
UniParc:
UPI0000DA325F
EMBL:
AABR07066803,
CH473987
Ensembl:
ENSRNOG00000018232
KO:
rno:501099
|
| Nucleutide sequences |
EMBL-CDS:
EDM18828.1
Gene_ORFName:
rCG_43683
Ensembl_TRS:
ENSRNOT00000061430
|
| Protein sequencees |
Ensembl_PRO:
ENSRNOP00000058149
RefSeq:
NP_001102772.1,
XP_006244619.1,
XP_006244620.1
|
| Others |
UniRef100:
UniRef100_D3ZHH8
UniRef90:
UniRef90_Q9JM73
UniRef50:
UniRef50_Q9JM73
UniGene:
Rn.1501
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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