| Type | Description |
|---|---|
| Definition | prostaglandin-endoperoxide synthase 2 |
| Date | Results | Publications |
|---|---|---|
| 2019-10-12 10:04:00 | bradykinin activates via the PLD/PDK-1 pathway, which subsequently induces activation and translocation of ERK1 into the nucleus, and contributes to COX-2 expression for prostaglandin E2 synthesis in dermal fibroblasts. | 29867151 |
| 2017-12-02 11:40:00 | Increased iNOS, COX-2 and VEGF gene mRNA levels were found to be related with the histological grade of malignancy in dogs with mammary tumours. | 28956485 |
| 2017-02-18 11:37:00 | These findings demonstrate low renal COX-2 expression in CKD in young dogs, but whether this is correlated with disease pathogenesis remains unclear. | 27892876 |
| 2016-10-22 11:55:00 | These findings suggest that stimulation of MEK/ERK signaling pathway by NF-kappaB activation regulates IL-1beta-induced COX-2 expression and subsequent prostaglandin E2 release in canine dermal fibroblasts. | 26549149 |
| 2015-02-21 11:58:00 | provide a rationale for further investigation of COX-2 expression in canine lymphoma for prognostic, chemopreventive and chemotherapeutic purposes | 24813155 |
| Type | IDs |
|---|---|
| Synonymous | COX-2 |
| Gene |
UniProtKB-ID:
Q8SPQ9_CANLF
UniprotKB:
Q8SPQ9
UniParc:
UPI0000037706
EMBL:
AAEX03005167,
HQ110882,
AY044905
Ensembl:
ENSCAFG00000013762
KO:
cfa:442942
|
| Nucleutide sequences |
EMBL-CDS:
AAK97783.1,
ADO27661.1
Ensembl_TRS:
ENSCAFT00000021841
|
| Protein sequencees |
Ensembl_PRO:
ENSCAFP00000020288
RefSeq:
XP_005622284.1,
NP_001003354.1
|
| Others |
UniRef100:
UniRef100_Q8SPQ9
UniRef90:
UniRef90_O02768
UniRef50:
UniRef50_Q05769
UniGene:
Cfa.3449
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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