例如:"NBL1", "4681", "drought"
收藏
44205 spen

44205

spen

split ends

protein-coding

Drosophila melanogaster

基因描述

Type Description
Definition split ends

研究结论

Date Results Publications
2019-03-02 10:47:00 Demonstrate that spen acts at multiple points in the intestinal stem cell (ISC) lineage with an ISC-intrinsic function in controlling early commitment events of the stem cells and functions in terminally differentiated cells to further limit the proliferation of ISCs. 30452449
2018-07-14 10:09:00 Yif1 is required for dendrite pruning of ddaC neurons but not for apoptosis of ddaF neurons. also, the Yif1-binding partner Yip1 is also crucial for dendrite pruning. Yif1 forms a protein complex with Yip1 in S2 cells and ddaC neurons. 29769219
2017-07-22 10:57:00 Spenito, a small Spen family member, counteracted Spen function in fat regulation. Finally, mouse Spen and Spenito transcript levels scaled directly with body fat in vivo, suggesting a conserved role in fat liberation and catabolism. This study demonstrates that Spen is a key regulator of energy balance and provides a molecular context to understand the metabolic defects that arise from Spen dysfunction. 28640815
2015-08-15 10:59:00 Spen is an important survival factor that ensures spatial control of the apoptotic wave that is necessary for the correct patterning and formation of the Drosophila eye. 25872184
2010-01-21 00:00:00 Dosage-sensitive genetic interactions further support a model of functional antagonism between NITO and SPEN during Drosophila eye development. 16547102

名称对应

Type IDs
Synonymous 136/24, BcDNA:GM01870, CG18497, Dmel\CG18497, E(E2F)2A, E(Raf)2A, E(Sev-CycE)2A, EK2-9, EY2-7, En(yan[ACT])2-7, SPEN, Spen, Splitends, l(2)03350, l(2)k06805, l(2)k07612, l(2)k08102, poc, rno, spe, yip1
Gene
UniProtKB-ID: SPEN_DROME, M9NCM6_DROME, M9PBZ3_DROME, M9PBJ8_DROME, M9PDR5_DROME
UniprotKB: Q8SX83, M9NCM6, M9PBZ3, M9PBJ8, M9PDR5
UniParc: UPI00001D8A81, UPI0000110169, UPI000011012C, UPI0000110171, UPI0002942AE5, UPI000237F7D2, UPI00029422C8, UPI0002941D4E
EMBL: AF184612, AF221715, AE014134, AY094788, AF188205
EnsemblGenome: FBgn0016977
KO: dme:Dmel_CG18497
Nucleutide sequences
EMBL-CDS: AAN10511.1, AAF34661.1, AAF51535.2, AAF13218.1, AAF26299.1, AAF51534.2, AAM11141.1, AFH03493.1, AGB92341.1, AGB92340.1, AGB92339.1, AGB92342.1
Gene_ORFName: CG18497, Dmel_CG18497, CG18497, CG18497, Dmel_CG18497, Dmel_CG18497, CG18497, Dmel_CG18497, CG18497
EnsemblGenome_TRS: FBtr0078121, FBtr0078122, FBtr0078123, FBtr0306341, FBtr0330652, FBtr0332337, FBtr0332336, FBtr0330653
Protein sequencees
EnsemblGenome_PRO: FBpp0077782, FBpp0077781, FBpp0077780, FBpp0297434, FBpp0303502, FBpp0304614, FBpp0304613, FBpp0303503
RefSeq: NP_001259803.1, NP_722615.1, NP_524718.2, NP_001259805.1, NP_001259802.1, NP_001245816.1, NP_722616.1, NP_001259804.1
Others
UniRef100: UniRef100_M9PBJ8, UniRef100_Q8SX83, UniRef100_M9PDR5, UniRef100_M9NCM6, UniRef100_M9PBZ3
UniRef90: UniRef90_Q8SX83
UniRef50: UniRef50_Q8SX83
UniGene: Dm.3450

全选

{{proteinIndex+1}}
mRNA Protein UniprotKB Description
Refseq {{protein.nucleotideVersion}}

Ensembl: {{protein.nucleotideEnsembl}}

{{protein.proteinVersion}}

Ensembl: {{protein.proteinEnsembl}}

{{uniprot}}
Definition: {{{protein.definition}}}

Transcript Veriant:{{protein.transcriptVeriant}}

Status: {{protein.status}}

Location ( {{protein.positionStart}}..{{protein.positionEnd}} )

暂无数据

研究热度

热点单位
排名 科研单位 文献
{{affIndex+1}}

{{aff.value}}

{{aff.size}}

目前还没有研究热点单位

热点人员
排名 研究人员 文献
{{authorIndex+1}}

{{author.value}}

{{author.size}}

目前还没有研究热点人员