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43847 KLK14

43847

KLK14

kallikrein related peptidase 14

protein-coding

Homo sapiens

基因描述

Type Description
Definition kallikrein related peptidase 14

研究结论

Date Results Publications
2021-02-13 13:25:00 Kallikrein-Related Peptidase 14 Activates Zymogens of Membrane Type Matrix Metalloproteinases (MT-MMPs)-A CleavEx Based Analysis. 32575583
2021-02-06 13:52:00 The molecular function of kallikrein-related peptidase 14 demonstrates a key modulatory role in advanced prostate cancer. 31630475
2021-01-09 13:26:00 Transgenic Kallikrein 14 Mice Display Major Hair Shaft Defects Associated with Desmoglein 3 and 4 Degradation, Abnormal Epidermal Differentiation, and IL-36 Signature. 32169475
2018-06-16 10:35:00 There was no significant association of KLK13 and KLK14 mRNA expression with the clinical factors ascitic fluid volume or residual tumor mass. High KLK14 mRNA levels were significantly associated with prolonged PFS (HR = 0.44, P = 0.017) and showed a trend towards significance for OS (HR = 0.55, P = 0.070). 29546479
2018-04-14 11:08:00 In this work, KLK14 binding to either hepatocyte growth factor activator inhibitor type-1 (HAI-1) or type-2 (HAI-2) was essayed using homology modeling, molecular dynamic simulations and free-energy calculations through MM/PBSA and MM/GBSA. KLK14 was successfully modeled. 28817220

名称对应

Type IDs
Synonymous KLK-L6
Gene
UniProtKB-ID: KLK14_HUMAN, A0A1R3UHJ7_HUMAN, A0A024R4M6_HUMAN
UniprotKB: Q9P0G3, A0A1R3UHJ7, A0A024R4M6
UniParc: UPI000004CA08, UPI0000D48B96
EMBL: AF161221, BC074904, CH471135, EU091477, AF283670, AF283669, AC011473, BC114614, LT631564, BC074905
Ensembl: ENSG00000129437
KO: hsa:43847
Nucleutide sequences
EMBL-CDS: AAD50773.2, EAW71982.1, AAK48524.1, ABU63131.1, AAH74905.2, AAH74904.2, AAG23260.1, AAK48523.1, AAI14615.2, SFW93211.1, EAW71983.1
Gene_ORFName: hCG_1647899
Ensembl_TRS: ENST00000391802, ENST00000650543, ENST00000156499
Protein sequencees
Ensembl_PRO: ENSP00000375678, ENSP00000497141, ENSP00000156499
RefSeq: XP_016882309.1, NP_001298111.2, NP_071329.3, NP_001356704.1
Others
UniRef100: UniRef100_Q9P0G3
UniRef90: UniRef90_Q9P0G3
UniRef50: UniRef50_Q9P0G3
UniGene: Hs.283925

全选

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