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43718 pygo

43718

pygo

pygopus

protein-coding

Drosophila melanogaster

基因描述

Type Description
Definition pygopus

研究结论

Date Results Publications
2016-06-11 11:32:00 The authors use a proteomics approach to discover the Chip/LDB-SSDP (ChiLS) complex as the ligand specifically binding to NPF motif of Pygo proteins. 26312500
2014-09-27 11:24:00 results are consistent with the idea that pygo functions independently of canonical Wnt signaling in the differentiation of the adult interchamber cardiac valves 24265259
2014-09-20 11:09:00 humanized fly Pygo derepresses Notch targets, implying an inherent Notch-related function of classical Pygo orthologs, disabled in fly Pygo, which thus appears dedicated to Wnt signaling. 24183574
2014-05-17 14:56:00 Double knockdown of pygo and Ca2+/calmodulin-dependent protein kinase II caused additional arrhythmia compared with pygo knockdown alone, suggesting that some of the effects of pygo are mediated by Ca2+ signaling. 24046329
2010-01-21 00:00:00 Pygo is an essential component in the Wg/Wnt signal transduction pathway and is likely to act as a transcription co-activator required for the nuclear function of Arm/beta-catenin 12163411

名称对应

Type IDs
Synonymous BEST:LD21971, CG11518, Dm Pygo, Dmel\CG11518, Pygo, anon-WO02077023.1, dPygo, gam, pNB5.2, pyg, pypo
Gene
UniProtKB-ID: PYGO_DROME
UniprotKB: Q9V9W8
UniParc: UPI00000510CF
EMBL: AY075095, AE014297, AF457206, AY058500
EnsemblGenome: FBgn0043900
KO: dme:Dmel_CG11518
Nucleutide sequences
EMBL-CDS: AAL79357.1, AAL91369.1, AAL13729.1, AAF57161.1
Gene_ORFName: CG11518
EnsemblGenome_TRS: FBtr0085806
Protein sequencees
EnsemblGenome_PRO: FBpp0085167
RefSeq: NP_651872.1
Others
UniRef100: UniRef100_Q9V9W8
UniRef90: UniRef90_Q9V9W8
UniRef50: UniRef50_Q9V9W8
UniGene: Dm.5270

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