| Type | Description |
|---|---|
| Definition | dj-1beta |
| Date | Results | Publications |
|---|---|---|
| 2013-03-02 13:17:00 | Dj-1beta regulates oxidative stress, insulin-like signaling and development in Drosophila melanogaster. | 22983063 |
| 2012-07-14 10:33:00 | the oxidation of conserved cysteine residue to its sulfinate form (Cys-SO(2)(-)) results in considerable thermal stabilization of both Drosophila DJ-1beta and human DJ-1 | 22515803 |
| 2010-07-05 11:42:00 | Flies deleted for DJ-1 manifest similar defects as pink1 and parkin mutants: male sterility, shortened lifespan, and reduced climbing ability. | 20457924 |
| 2010-01-21 00:00:00 | Data show that human DJ-1 rescues flies mutant for DJ-1b; a conserved cysteine in is critical for antioxidant function, and suggest that overoxidation of DJ-1 with age and exposure to oxidants can cause inactivation. | 16894167 |
| 2010-01-21 00:00:00 | Loss-of-function DJ-1beta mutants demonstrated an extended survival of dopaminergic neurons and resistance to paraquat stress, but showed acute sensitivity to hydrogen peroxide treatment. | 16139214 |
| Type | IDs |
|---|---|
| Synonymous | CG1349, DJ-1, DJ-1B, DJ-1b, DJ-1beta, Dmel\CG1349, dj1-beta |
| Gene |
UniProtKB-ID:
DJ1B_DROME
UniprotKB:
Q9VA37
UniParc:
UPI000007EBFC,
UPI0000007665
EMBL:
AB079599,
AE014297,
AY060670
EnsemblGenome:
FBgn0039802
KO:
dme:Dmel_CG1349
|
| Nucleutide sequences |
EMBL-CDS:
AAL28218.1,
AAF57086.3,
BAB84672.1
Gene_ORFName:
CG1349
EnsemblGenome_TRS:
FBtr0445215
|
| Protein sequencees |
EnsemblGenome_PRO:
FBpp0401456
RefSeq:
NP_651825.4
|
| Others |
UniRef100:
UniRef100_Q9VA37
UniRef90:
UniRef90_Q9VA37
UniRef50:
UniRef50_Q9VA37
UniGene:
Dm.3914
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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