| Type | Description |
|---|---|
| Definition | lethal (3) malignant brain tumor |
| Date | Results | Publications |
|---|---|---|
| 2018-05-26 11:09:00 | L(3)mbt secures tissue identity by preventing the simultaneous expression of original identity markers and tissue-specific misexpression signatures. | 29511022 |
| 2017-05-13 10:46:00 | CRISPR-mediated loss of function of lethal (3) malignant brain tumor [l(3)mbt] leads to ectopic activation of the germ-specific ping-pong cycle in ovarian somatic cells | 27474440 |
| 2015-05-02 11:42:00 | Data show that L(3)mbt chromosomal targeting requires proteins of a site-specific DNA binding complex Myb-MuvB (MMB core component Mip130)/DREAM. | 25249635 |
| 2014-05-17 10:15:00 | Data indicate that germline genes, some of which drive oncogenesis in Drosophila melanogaster, are similarly ectopically activated in a wide range of human cancers. | 24243547 |
| 2011-12-10 10:51:00 | Data show that brain tumours in l(3)mbt mutants originate from overproliferation of neuroepithelial cells in the optic lobes caused by derepression of target genes in the Salvador-Warts-Hippo (SWH) pathway. | 21857667 |
| Type | IDs |
|---|---|
| Synonymous | CG5954, Dmel\CG5954, L(3)MBT, L(3)MBT/LIN-61, L(3)mbt, L3mbt, MBT, dL(3)mbt, dl(3)MBT, l(3)malignant braintumor, mbt |
| Gene |
UniProtKB-ID:
Q9VB52_DROME
UniprotKB:
Q9VB52
UniParc:
UPI000007A8F4
EMBL:
AE014297,
AY051653
EnsemblGenome:
FBgn0002441
KO:
dme:Dmel_CG5954
|
| Nucleutide sequences |
EMBL-CDS:
AAK93077.1,
AAN14107.1
Gene_ORFName:
CG5954,
Dmel_CG5954
EnsemblGenome_TRS:
FBtr0085175
|
| Protein sequencees |
EnsemblGenome_PRO:
FBpp0084545
RefSeq:
NP_733209.1
|
| Others |
UniRef100:
UniRef100_Q9VB52
UniRef90:
UniRef90_Q9VB52
UniRef50:
UniRef50_Q9VB52
UniGene:
Dm.4525
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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