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4168 MCF2

4168

MCF2

MCF.2 cell line derived transforming sequence

protein-coding

Homo sapiens

基因描述

Type Description
Definition MCF.2 cell line derived transforming sequence

研究结论

Date Results Publications
2020-05-30 10:14:00 we elucidate a mechanism through which the DBL family members MCF2 and VAV1 act to drive drug resistance in human BRAFV600E-mutant melanoma cells 31416844
2016-02-27 11:40:00 Results support a role for Dbl oncogene in mammary epithelial cell differentiation and transformation and suggest the relevance of GEF deregulation in tumor onset and progression. 25723869
2013-03-16 11:10:00 Phosphoinositide 3-kinase C2beta regulates RhoA and the actin cytoskeleton through an interaction with Dbl 22984590
2011-10-22 11:15:00 Dbl is regulated by hamartin through association with ezrin. 21712385
2011-07-02 11:11:00 proto-oncogene dbl is not a major target for sporadic testicular germ cell tumors 19373475

名称对应

Type IDs
Synonymous ARHGEF21, DBL
Gene
UniProtKB-ID: MCF2_HUMAN, B2R9S6_HUMAN
UniprotKB: P10911, B2R9S6
UniParc: UPI000006CDFC, UPI0001C33996, UPI000045789E, UPI0001750727, UPI0001C33995, UPI00000725B8, UPI000045789D
EMBL: AB085902, AL117234, AK316416, AK302957, X13230, AK296488, AK313900, J03639, X12556, AL161777, AB085901, AL033403, CH471150
Ensembl: ENSG00000101977
KO: hsa:4168
Nucleutide sequences
EMBL-CDS: CAA31617.1, BAC41201.1, BAC41200.1, CAA31069.1, AAA52172.1, CAB55301.1, BAH13855.1, BAH12371.1, BAH14787.1, EAW88430.1, EAW88427.1, BAG36623.1
Ensembl_TRS: ENST00000519895, ENST00000414978, ENST00000370573, ENST00000370576, ENST00000536274, ENST00000338585
Protein sequencees
Ensembl_PRO: ENSP00000438155, ENSP00000342204, ENSP00000359608, ENSP00000359605, ENSP00000397055, ENSP00000430276
RefSeq: NP_001165347.1, XP_016885019.1, NP_001165349.1, XP_005262470.1, XP_016885021.1, XP_016885018.1, NP_001165350.1, NP_001093325.1, NP_001165348.1, NP_005360.3, XP_011529641.1, XP_016885020.1
Others
UniRef100: UniRef100_B2R9S6, UniRef100_P10911
UniRef90: UniRef90_P10911
UniRef50: UniRef50_P10911
UniGene: Hs.387262
CCDS: CCDS55517.1, CCDS48175.1, CCDS55516.1, CCDS55514.1, CCDS14667.1, CCDS55515.1

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