| Type | Description |
|---|---|
| Definition | MCC regulator of WNT signaling pathway |
| Date | Results | Publications |
|---|---|---|
| 2019-08-03 13:30:00 | This study provided new evidence of epistatic association of VAMP5 and MCC with increased risk of Hirschsprung disease | 29695640 |
| 2019-02-02 12:05:00 | Alterations (deletion/methylation/mutation/expression) of MCC and CTNNBIP1 were analyzed in breast cancer patients (N=120) followed by expression/mutation analysis of beta-catenin. The alterations of MCC/CTNNBIP1 showed significant correlation with increased nuclear beta-catenin/p-beta-catenin(Y654) expression. | 27208794 |
| 2018-10-13 10:49:00 | Study described a novel tumor suppressor function of MCC in the regulation of E-cadherin mediated cell-cell adhesion in colorectal cancer cells. | 29035389 |
| 2018-05-19 12:12:00 | Data suggest that millisecond dynamic changes in PDZ1 domain conformation are responsible for higher affinity of scribble PDZ1 for phosphorylated ligands; oligopeptide fragments of RPS6KA2 and MCC were used as ligands in these nuclear magnetic resonance chemical shift experiments. (RPS6KA2 = ribosomal protein S6 kinase 2; MCC = mutated in colorectal cancer protein) | 29144123 |
| 2018-04-07 11:17:00 | MCC might confer alterative genetic susceptibility to colorectal cancer in individuals with schizophrenia promising to shed more light on the relationship between schizophrenia and cancer progression. | 27226254 |
| Type | IDs |
|---|---|
| Synonymous | MCC1 |
| Gene |
UniProtKB-ID:
CRCM_HUMAN
UniprotKB:
P23508
UniParc:
UPI000013E7E1,
UPI00015E06EA
EMBL:
AC010431,
AC126917,
AC008536,
BC009279,
M62397,
AC106750,
AC079465,
AC093208,
AK128596,
CH471086,
BC018919
Ensembl:
ENSG00000171444
KO:
hsa:4163
|
| Nucleutide sequences |
EMBL-CDS:
EAW48984.1,
AAA52069.1,
BAC87521.1,
AAH09279.1,
AAH18919.1,
EAW48986.1
Ensembl_TRS:
ENST00000302475,
ENST00000408903
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000386227,
ENSP00000305617
RefSeq:
XP_024301818.1,
XP_016864962.1,
XP_024301820.1,
XP_016864963.1,
NP_002378.2,
XP_005272048.1,
XP_024301817.1,
XP_024301819.1,
NP_001078846.2
|
| Others |
UniRef100:
UniRef100_P23508
UniRef90:
UniRef90_P23508
UniRef50:
UniRef50_P23508
UniGene:
Hs.593171
CCDS:
CCDS43351.1,
CCDS4111.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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