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40240 eRF1

40240

eRF1

eukaryotic translation release factor 1

protein-coding

Drosophila melanogaster

基因描述

Type Description
Definition eukaryotic translation release factor 1

研究结论

Date Results Publications
2020-08-01 10:10:00 Overexpression of eRF1 ameliorates repeat expansion in C9orf72 toxicity in vivo. 32059759
2019-12-14 12:03:00 In both Neurospora and Drosophila cells, codon usage plays an important role in regulating mRNA translation efficiency. We found that the rare codon-dependent premature termination is mediated by the translation termination factor eRF1, which recognizes ribosomes stalled on rare sense codons. Silencing of eRF1 expression resulted in codon usage-dependent changes in protein expression 31410471

名称对应

Type IDs
Synonymous CG5605, Dm0184, Dmel\CG5605, Group J, group J, l(3)00103, l(3)05637, l(3)77ABb, l(3)neo28
Gene
UniProtKB-ID: ERF1_DROME, D1Z373_DROME, M9PD27_DROME, M9PFR9_DROME
UniprotKB: Q9VPH7, D1Z373, M9PD27, M9PFR9
UniParc: UPI00000073E6, UPI000293F715, UPI00017FC9B4
EMBL: BT120010, AE014296, AY069511, BT120009
EnsemblGenome: FBgn0036974
KO: dme:Dmel_CG5605
Nucleutide sequences
EMBL-CDS: AAN12122.1, AAN12121.1, AAO41278.1, AAN12123.1, AAF51574.2, AAL39656.1, ACZ94122.1, ACZ94121.1, AGB94797.1, AGB94798.1
Gene_ORFName: CG5605, Dmel_CG5605, CG5605, Dmel_CG5605, CG5605
EnsemblGenome_TRS: FBtr0078176, FBtr0078174, FBtr0078177, FBtr0078173, FBtr0078175, FBtr0078178, FBtr0078178, FBtr0078175, FBtr0078174, FBtr0078177, FBtr0078173, FBtr0078176, FBtr0331817, FBtr0331818
Protein sequencees
EnsemblGenome_PRO: FBpp0077831, FBpp0077832, FBpp0077836, FBpp0077834, FBpp0077835, FBpp0077833, FBpp0077836, FBpp0077832, FBpp0077833, FBpp0077831, FBpp0077834, FBpp0077835, FBpp0304201, FBpp0304202
RefSeq: NP_001262104.1, NP_001262105.1, NP_788547.1, NP_730520.1, NP_730518.1, NP_649210.1, NP_730519.1, NP_730517.1
Others
UniRef100: UniRef100_M9PD27, UniRef100_M9PFR9, UniRef100_Q9VPH7
UniRef90: UniRef90_Q9VPH7, UniRef90_M9PFR9
UniRef50: UniRef50_M9PFR9, UniRef50_Q9VPH7
UniGene: Dm.2095

全选

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研究热度

热点单位
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