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40155 SREBP

40155

SREBP

Sterol regulatory element binding protein

protein-coding

Drosophila melanogaster

基因描述

Type Description
Definition Sterol regulatory element binding protein

研究结论

Date Results Publications
2019-07-13 11:52:00 constitutive activation of the TOR-pathway target and lipogenesis factor Sterol regulatory element binding protein (SREBP) also resulted in GSC loss, whereas inhibition of SREBP rescued GSC loss triggered by depletion of dMfn. 31160709
2018-07-21 10:53:00 The dendrite simplification in srebp mutant nociceptive neurons is accompanied by hypersensitivity of srebp mutant larvae to noxious stimuli. 29262315
2016-04-16 12:05:00 During the larval-pupal transition, the levels of CDK8 inversely correlate with the activity of sterol regulatory element binding protein. 26222308
2015-04-04 10:45:00 TORC1-SREBP serves to integrate signals promoting growth and G1-S progression in order to maintain enodplasmic reticulum function during cell proliferation. 25007267
2010-09-20 11:05:00 dScap and dS2P, essential components of the SREBP activation machinery in mammalian cells, are dispensable in Drosophila owing to different compensatory mechanisms. 20176975

名称对应

Type IDs
Synonymous CG8522, Dmel\CG8522, HLH106, HlH106, SREBF1, Srebp, dSREBP, dSrebp, dsrebp, l(3)76BDw, srebp
Gene
UniProtKB-ID: Q9VW37_DROME
UniprotKB: Q9VW37
UniParc: UPI000007B6EA
EMBL: BT010285, AE014296
EnsemblGenome: FBgn0261283
KO: dme:Dmel_CG8522
Nucleutide sequences
EMBL-CDS: AAN11631.1, AGB94757.1, AAF49115.1, AAN11632.1, AAQ23603.1
Gene_ORFName: Dmel_CG8522, CG8522
EnsemblGenome_TRS: FBtr0074874, FBtr0074873, FBtr0074875, FBtr0333877
Protein sequencees
EnsemblGenome_PRO: FBpp0074644, FBpp0074642, FBpp0074643, FBpp0306009
RefSeq: NP_524166.2, NP_001262064.1, NP_730450.1, NP_730449.1
Others
UniRef100: UniRef100_Q9VW37
UniRef90: UniRef90_Q9VW37
UniRef50: UniRef50_Q9VW37
UniGene: Dm.7945

全选

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研究热度

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