| Type | Description |
|---|---|
| Definition | amelotin |
| Date | Results | Publications |
|---|---|---|
| 2020-10-03 12:53:00 | Amelotin is expressed in retinal pigment epithelium and localizes to hydroxyapatite deposits in dry age-related macular degeneration. | 32160961 |
| 2018-09-22 12:05:00 | TNF-alpha stimulates AMTN gene transcription in human gingival epithelial cells via C/EBP1, C/EBP2, and YY1 elements in the human AMTN gene promoter. | 29282478 |
| 2017-12-23 10:51:00 | Results show that AMTN and KLK4 are not essential for biological processes outside of the dentition or during the secretory stage of amelogenesis. Both KLK4 and AMTN proved to be essential for the maturation of dental enamel, a process that requires the removal of extracellularmatrix proteins and the deposition of ions on the sides of enamel crystallites. | 26620968 |
| 2017-07-15 11:26:00 | This study demonstrates for the first time that AMTN mutations cause non-syndromic human Amelogenesis imperfecta (AI) and explores the human phenotype, comparing it with that of mice with disrupted Amtn function. | 27412008 |
| 2016-03-19 10:54:00 | AMTN has a direct influence on biomineralization by promoting hydroxyapatite mineralization. | 25407797 |
| Type | IDs |
|---|---|
| Synonymous | AI3B, UNQ689 |
| Gene |
UniProtKB-ID:
AMTN_HUMAN,
F1T0L8_HUMAN
UniprotKB:
Q6UX39,
F1T0L8
UniParc:
UPI000022C632,
UPI00000389F3
EMBL:
AY358528,
BC121812,
AB593161,
BC121817
Ensembl:
ENSG00000187689
KO:
hsa:401138
|
| Nucleutide sequences |
EMBL-CDS:
AAQ88892.1,
AAI21813.1,
AAI21818.1,
BAJ84092.1
Gene_ORFName:
UNQ689/PRO1329
Ensembl_TRS:
ENST00000504451,
ENST00000339336
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000422452,
ENSP00000341013
RefSeq:
NP_997722.1,
NP_001273660.1
|
| Others |
UniRef100:
UniRef100_Q6UX39
UniRef90:
UniRef90_Q6UX39
UniRef50:
UniRef50_Q6UX39
UniGene:
Hs.453069
CCDS:
CCDS3542.1,
CCDS68716.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
{{protein.nucleotideVersion}}
Ensembl: {{protein.nucleotideEnsembl}} |
{{protein.proteinVersion}}
Ensembl: {{protein.proteinEnsembl}} |
{{uniprot}} , |
Definition: {{{protein.definition}}}Transcript Veriant:{{protein.transcriptVeriant}} Status: {{protein.status}} |
||||
| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
||||
暂无数据
| 排名 | 科研单位 | 文献 |
|---|---|---|
| {{affIndex+1}} |
{{aff.value}} |
{{aff.size}} |
目前还没有研究热点单位
| 排名 | 研究人员 | 文献 |
|---|---|---|
| {{authorIndex+1}} |
{{author.value}} |
{{author.size}} |
目前还没有研究热点人员