| Type | Description |
|---|---|
| Definition | myostatin |
| Date | Results | Publications |
|---|---|---|
| 2020-08-29 12:45:00 | Shift from slow- to fast-twitch muscle fibres in skeletal muscle of newborn heterozygous and homozygous myostatin-knockout piglets. | 31104696 |
| 2019-11-23 11:08:00 | Results show that the fecal microbial composition is very similar between myostatin loss-of-function mutation (MSTN-/-) Meishan pigs and wild type Meishan pigs. | 30645618 |
| 2019-08-17 10:45:00 | A mutant-type myostatin propeptide (D75A-MSPP) was superior to WT-MSPP in effectively enhancing myofiber growth due to the highly resistant to proteolytic cleavage by the bone morphogenetic protein-1/tolloid (BMP-1/TLD) and thus has potential applications for clinical muscle wasting diseases or for increasing muscle mass in meat-producing animals. | 30921567 |
| 2019-03-16 12:59:00 | This MSTN mutation is an example of putative balancing selection in livestock, providing a plausible explanation for the lack of disrupting MSTN mutations in pigs despite many generations of selection for lean growth | 30699111 |
| 2018-05-19 11:28:00 | Report the generation of isozygous, functional myostatin (MSTN) knockout cloned pigs free of selectable marker gene (SMG) by CRISPR/Cas9 and Cre/LoxP. CRISPR/Cas9-mediated homologous recombination (HR) was exploited to knock out (KO) one allele of MSTN in pig primary cells. | 27530319 |
| Type | IDs |
|---|---|
| Synonymous | GDF8, GDF8:MSTN |
| Gene |
UniProtKB-ID:
Q6SVB3_PIG
UniprotKB:
Q6SVB3
UniParc:
UPI00004280D2
EMBL:
AY448008
KO:
ssc:399534
|
| Nucleutide sequences |
EMBL-CDS:
AAR18245.2
|
| Protein sequencees |
RefSeq:
NP_999600.2
|
| Others |
UniRef100:
UniRef100_Q6SVB3
UniRef90:
UniRef90_O14793
UniRef50:
UniRef50_O14793
UniGene:
Ssc.23498
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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