| Type | Description |
|---|---|
| Definition | DNA topoisomerase II binding protein 1 L homeolog |
| Date | Results | Publications |
|---|---|---|
| 2017-06-24 12:19:00 | Data show that TopBP1 and Nbs1 associate with the N-terminal region of Mdc1 in egg extracts. | 27590578 |
| 2016-11-19 10:04:00 | The critical ATR activator, TopBP1, senses DNA damage and stalled replication forks to initiate assembly of checkpoint signaling complexes. | 27129245 |
| 2014-11-08 13:45:00 | TopBP1's C-terminal motif containing a putative nuclear localization signal was required for Importin beta interaction and that CT100 of Importin beta was required for TopBP1 interaction. | 24440306 |
| 2013-08-31 11:19:00 | these findings indicate that WDR18 is a bona fide checkpoint protein and that WDR18 works together with TopBP1 to promote DNA damage checkpoint signaling. | 23333389 |
| 2013-06-15 11:35:00 | MRN (MRE11-RAD50-NBS1) complex has role in ATR activation via TOPBP1 recruitment. | 23582259 |
| Type | IDs |
|---|---|
| Synonymous | TopBP1-A, TopBP1-B, Xmus101, XtopBP, cut5, mus101, top2bp1, topbp1 |
| Gene |
UniProtKB-ID:
TOB1A_XENLA,
A0A1L8FWJ6_XENLA
UniprotKB:
Q800K6,
A0A1L8FWJ6
UniParc:
UPI000189349B,
UPI00084DC01C
EMBL:
BC170557,
BC170556,
CM004476,
AB091779
KO:
xla:398573
|
| Nucleutide sequences |
EMBL-CDS:
BAC65235.1,
AAI70556.1,
AAI70557.1,
OCT75946.1
Gene_ORFName:
XELAEV_18031132mg
|
| Protein sequencees |
RefSeq:
NP_001082568.1,
XP_018121832.1
|
| Others |
UniRef100:
UniRef100_A0A1L8FWJ6,
UniRef100_Q800K6
UniRef90:
UniRef90_Q800K6
UniRef50:
UniRef50_Q800K6
UniGene:
Xl.11481
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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