| Type | Description |
|---|---|
| Definition | Cyclic-AMP response element binding protein A |
| Date | Results | Publications |
|---|---|---|
| 2020-02-01 12:47:00 | Loss of CrebA also partially suppresses mHtt effects on behavior and cell loss and restoration of CrebA can suppress Atx2 effects. Our results indicate a prominent role of Atx2 in mediating mHtt pathology, specifically via its regulation of CrebA, defining a novel molecular pathway in Huntington's disease pathogenesis. | 31593562 |
| 2018-06-23 10:23:00 | Data suggest that CrebA is involved in regulation of infection tolerance in this species; expression of CrebA is regulated in the fat body upon infection; CrebA is required to survive infection and promotes tolerance of bacterial infection; CrebA deficiency leads to ER (endoplasmic reticulum) stress upon bacterial challenge. | 29394281 |
| 2018-03-26 09:39:00 | CrebA deficiency leads to ER stress upon bacterial challenge | 29394281 |
| 2010-12-11 10:08:00 | Drosophila CrebA directly binds the enhancers of secretory pathway genes and is both necessary and sufficient to activate expression of every secretory pathway component gene examined thus far. | 21041443 |
| 2010-08-23 11:43:00 | direct and indirect interactions of the hsromega transcripts with a variety of regulatory proteins like hnRNPs, CBP, proteasome, Drosophila inhibitor of apoptosis protein 1 (DIAP1) | 20065067 |
| Type | IDs |
|---|---|
| Synonymous | BBF-2, BBF2_DROME, BOX B Binding Factor-2, Bbbf2, BcDNA:SD05937, CG7450, CRE-BP, CREB, CREB-A, CREB-a, CREBA, Creb, Creb A, Creb-A, DM4, Dmel\CG7450, creb, crebA, dCREB-A, dCREBA, dCreb-A, dCrebA, l(3)03576 |
| Gene |
UniProtKB-ID:
CREBA_DROME,
Q1LZ07_DROME
UniprotKB:
P29747,
Q1LZ07
UniParc:
UPI00001E1B86
EMBL:
M87038,
BT011074,
BT025219,
AY122251,
X64429,
AE014296
EnsemblGenome:
FBgn0004396
KO:
dme:Dmel_CG7450
|
| Nucleutide sequences |
EMBL-CDS:
CAA45771.1,
AAF49621.2,
AAU21396.1,
AAA28427.1,
AAR82739.1,
ABF17910.1,
AAS64997.1
Gene_ORFName:
CG7450,
Dmel_CG7450,
CG7450
EnsemblGenome_TRS:
FBtr0075558,
FBtr0075557,
FBtr0075557,
FBtr0075558
|
| Protein sequencees |
EnsemblGenome_PRO:
FBpp0075311,
FBpp0089339,
FBpp0089339,
FBpp0075311
RefSeq:
NP_996096.1,
NP_524087.3
|
| Others |
UniRef100:
UniRef100_P29747
UniRef90:
UniRef90_P29747
UniRef50:
UniRef50_P29747
UniGene:
Dm.6979
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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