| Type | Description |
|---|---|
| Definition | transmembrane protein 189 |
| Date | Results | Publications |
|---|---|---|
| 2020-07-18 12:21:00 | these results assign the TMEM189 gene to plasmanylethanolamine desaturase and suggest that the previously characterized phenotype of Tmem189-deficient mice may be caused by a lack of plasmalogens. | 32209662 |
| 2020-04-18 12:10:00 | TMEM189 could functionally replace CarF in M. xanthus, and knockout of TMEM189 in a human cell line eliminated plasmalogens; study reveals TMEM189 as the long-sought desaturase for animal plasmalogen biosynthesis | 31604315 |
| 2011-09-14 12:13:00 | TMEM189 is a target gene of the BACH1 transcription factor according to ChIP-seq analysis in HEK 293 cells. | 21555518 |
| 2010-12-05 22:08:00 | Observational study of gene-disease association and gene-environment interaction. (HuGE Navigator) | 21048031 |
| Type | IDs |
|---|---|
| Synonymous | KUA |
| Gene |
UniProtKB-ID:
PDES1_HUMAN
UniprotKB:
A5PLL7
UniParc:
UPI000006ECAD,
UPI0000418DC4
EMBL:
AL034423,
AB044550,
AF155120,
BC142966,
AK023028
Ensembl:
ENSG00000240849
KO:
hsa:387521,
hsa:387522
|
| Nucleutide sequences |
EMBL-CDS:
BAB14364.1,
AAF08702.1,
AAI42967.1,
BAB18652.1
Ensembl_TRS:
ENST00000371652,
ENST00000371650
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000360713,
ENSP00000360715
RefSeq:
NP_001155977.2,
NP_954580.2
|
| Others |
UniRef100:
UniRef100_A5PLL7
UniRef90:
UniRef90_A5PLL7
UniRef50:
UniRef50_A5PLL7
UniGene:
Hs.744839
CCDS:
CCDS54473.1,
CCDS13428.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
{{protein.nucleotideVersion}}
Ensembl: {{protein.nucleotideEnsembl}} |
{{protein.proteinVersion}}
Ensembl: {{protein.proteinEnsembl}} |
{{uniprot}} , |
Definition: {{{protein.definition}}}Transcript Veriant:{{protein.transcriptVeriant}} Status: {{protein.status}} |
||||
| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
||||
暂无数据
| Pubmed编号 | 文献信息 | 发表日期 | 相关基因 |
|---|---|---|---|
| 32814053 |
Cell Rep Christian Haenig , Nir Atias , Alexander K Taylor , Arnon Mazza , Martin H Schaefer , Jenny Russ , Sean-Patrick Riechers , Shushant Jain , Maura Coughlin , Jean-Fred Fontaine , Brian D Freibaum , Lydia Brusendorf , Martina Zenkner , Pablo Porras , Martin Stroedicke , Sigrid Schnoegl , Kristin Arnsburg , Annett Boeddrich , Lucia Pigazzini , Peter Heutink , J Paul Taylor , Janine Kirstein , Miguel A Andrade-Navarro , Roded Sharan , Erich E Wanker |
2020-08-18 | - |
| 32209662 |
Proc Natl Acad Sci U S A Ernst R Werner , Markus A Keller , Sabrina Sailer , Katharina Lackner , Jakob Koch , Martin Hermann , Stefan Coassin , Georg Golderer , Gabriele Werner-Felmayer , Raphael A Zoeller , Nicolas Hulo , Johannes Berger , Katrin Watschinger |
2020-04-07 | - |
| 31604315 |
A bacterial light response reveals an orphan desaturase for human plasmalogen synthesis. Science Aránzazu Gallego-GarcÃa , Antonio J Monera-Girona , Elena Pajares-MartÃnez , Eva Bastida-MartÃnez , Ricardo Pérez-Castaño , Antonio A Iniesta , Marta Fontes , S Padmanabhan , Montserrat ElÃas-Arnanz |
2019-10-04 | - |
| 29180619 |
The STUbL RNF4 regulates protein group SUMOylation by targeting the SUMO conjugation machinery. Nat Commun Ramesh Kumar , Román González-Prieto , Zhenyu Xiao , Matty Verlaan-de Vries , Alfred C O Vertegaal |
2017-11-27 | - |
| 29117863 |
BMC Biol Nila Roy Choudhury , Gregory Heikel , Maryia Trubitsyna , Peter Kubik , Jakub Stanislaw Nowak , Shaun Webb , Sander Granneman , Christos Spanos , Juri Rappsilber , Alfredo Castello , Gracjan Michlewski |
2017-11-08 | - |
| 26496610 |
A human interactome in three quantitative dimensions organized by stoichiometries and abundances. Cell Marco Y Hein , Nina C Hubner , Ina Poser , Jürgen Cox , Nagarjuna Nagaraj , Yusuke Toyoda , Igor A Gak , Ina Weisswange , Jörg Mansfeld , Frank Buchholz , Anthony A Hyman , Matthias Mann |
2015-10-22 |
Cep85l,
Rcc1,
Zbtb48,
Bsdc1,
Kifc1,
Ccp110,
Ints4,
Slc6a8,
Cenpi,
Nup107,
Xpo1,
Fbxw11,
Tubg1,
Csnk1d,
Bap1,
Ptpn23,
Tecpr2,
Slain1,
Ankrd28,
Prkaa1,
Espl1,
Gbf1,
Cdc20,
Cenpf,
Trip11,
Mbd5,
Kif22,
Dut,
Srsf1,
Actb,
Spred2,
Akt2,
Mta1,
Tgs1,
Pip4k2c,
Ankfy1,
Apc,
Ar,
Rhoa,
Atp2a2,
Atp5a1,
Atp7a,
Cep131,
Bach1,
Bcl7c,
Bmpr1a,
Brca1,
Bub1,
Bub1b,
C1qbp,
Anxa2,
Calu,
Cbx1,
Cbx4,
Cct2,
Cct3,
Cct4,
Cct7,
Cct8,
Cd2ap,
Cdk1,
Cdc37,
Cdh1,
Chek1,
Cit,
Copa,
Crebbp,
Cry1,
Csk,
Smc3,
Dctn1,
Ddb1,
Cdk2ap1,
Mapre1,
Ect2,
Eef1a1,
Eif3a,
Mark2,
Evpl,
Ewsr1,
Wdr5,
Dclre1b,
Fbl,
Fgfr1,
Flot1,
Flot2,
B4galt1,
Gnb1,
Gspt1,
Hdac6,
Herc2,
Hsf1,
Hsph1,
Elavl1,
Id2,
Cyr61,
Cep250,
Insr,
Eif3e
|
| 22939629 |
A census of human soluble protein complexes. Cell Pierre C Havugimana , G Traver Hart , Tamás Nepusz , Haixuan Yang , Andrei L Turinsky , Zhihua Li , Peggy I Wang , Daniel R Boutz , Vincent Fong , Sadhna Phanse , Mohan Babu , Stephanie A Craig , Pingzhao Hu , Cuihong Wan , James Vlasblom , Vaqaar-un-Nisa Dar , Alexandr Bezginov , Gregory W Clark , Gabriel C Wu , Shoshana J Wodak , Elisabeth R M Tillier , Alberto Paccanaro , Edward M Marcotte , Andrew Emili |
2012-08-31 |
SRB2,
TRA1,
MED6,
CDH2,
DDTL,
ABI1,
SRA1,
UQCRFS1P1,
SNRPGP15,
ZNF316,
LOC100132057,
PDCD6IP,
PDCD6,
MED16,
PIGK,
WASH1,
CHAF1A,
TOM1L1,
HMGXB4,
RANBP9,
SMC4,
UBA2,
SAE1,
FARSB,
ABCB6,
ABCF2,
TIMM23B,
SCAMP3,
DPP3,
HUWE1,
TSSC4,
PDCD7,
USH1C,
PQBP1,
ARPC5,
ARPC4,
ARPC3,
ARPC1B,
ACTR3,
ACTR2,
NUBP2,
TSFM,
PPIF,
ARPC2,
RAD50,
PREB,
ACTR1B,
ACTR1A,
RASGRP1,
LRPPRC,
PDIA6,
TRAP1,
RBM12,
G3BP1,
SUGP2,
TRIM28,
WASF2,
SLC25A13,
SORBS3,
ALYREF,
TXNDC9,
CDK4,
PRMT3,
PSME3,
MPHOSPH6,
CDK5,
NUTF2,
EIF1,
FLOT1,
PSMD14,
CDK7,
ADAM10,
PLIN3,
STX6,
MSLN,
HNRNPR,
MRPS31,
TIMM17B,
RIDA,
POP7,
SRRM1,
CDK9,
STAM2,
SF3B4,
ZMPSTE24,
STUB1,
UBE4B,
BET1,
CWC27,
SAP18,
SMNDC1,
BCAS2,
EIF1B,
SF3A1,
MAEA,
KATNB1,
TCIRG1,
RTN3,
LANCL1
|
| 21873635 |
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics Pascale Gaudet , Michael S Livstone , Suzanna E Lewis , Paul D Thomas |
2011-09-01 | - |
| 21555518 |
J. Biol. Chem. Hans-Jörg Warnatz , Dominic Schmidt , Thomas Manke , Ilaria Piccini , Marc Sultan , Tatiana Borodina , Daniela Balzereit , Wasco Wruck , Alexey Soldatov , Martin Vingron , Hans Lehrach , Marie-Laure Yaspo |
2011-07-01 |
BCL2L11,
CDK6,
COPS6,
SLX4IP,
SSC4D,
SLC25A10,
CTSL,
ADAMTS17,
AFG3L1P,
EWSR1,
FGF1,
ALDOA,
CLSTN1,
SLC7A11,
FTH1,
FTL,
RHBDD3,
GCLC,
GCLM,
GPI,
SLC9A9,
ANXA2P2,
HMOX1,
IFRD1,
ITPR2,
TMEM189,
TEX19,
MAFG,
MAPT,
ME1,
NQO2,
FAM49B,
MXRA8,
LRRC8D,
SLC48A1,
PSAP,
VTRNA1-2,
VTRNA1-1,
BACH1,
KIAA1549,
TTC23,
SMARCA4,
TFE3,
TKT,
TNFAIP2,
TNFRSF1A,
PHLDA2,
ZNF3,
CALM1,
ST8SIA2,
NPRL3,
TRIM56,
CFAP74,
SYNJ2,
SQSTM1,
BICDL1,
HTRA3,
SDC3,
SEMA3E,
NUP153
|
| 21565611 |
Mapping the NPHP-JBTS-MKS protein network reveals ciliopathy disease genes and pathways. Cell Liyun Sang , Julie J Miller , Kevin C Corbit , Rachel H Giles , Matthew J Brauer , Edgar A Otto , Lisa M Baye , Xiaohui Wen , Suzie J Scales , Mandy Kwong , Erik G Huntzicker , Mindan K Sfakianos , Wendy Sandoval , J Fernando Bazan , Priya Kulkarni , Francesc R Garcia-Gonzalo , Allen D Seol , John F O'Toole , Susanne Held , Heiko M Reutter , William S Lane , Muhammad Arshad Rafiq , Abdul Noor , Muhammad Ansar , Akella Radha Rama Devi , Val C Sheffield , Diane C Slusarski , John B Vincent , Daniel A Doherty , Friedhelm Hildebrandt , Jeremy F Reiter , Peter K Jackson |
2011-05-13 | - |
| 排名 | 科研单位 | 文献 |
|---|---|---|
| {{affIndex+1}} |
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| 排名 | 研究人员 | 文献 |
|---|---|---|
| {{authorIndex+1}} |
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