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3813 KIR3DS1

3813

KIR3DS1

killer cell immunoglobulin like receptor, three Ig domains and short cytoplasmic tail 1

protein-coding

Homo sapiens

基因描述

Type Description
Definition killer cell immunoglobulin like receptor, three Ig domains and short cytoplasmic tail 1

研究结论

Date Results Publications
2021-01-23 12:57:00 Diversity of KIR/HLA Genotypes and Their Association with Psoriasis Vulgaris in the Western Mexican Population. 32235781
2020-07-18 10:26:00 The KIR3DS1 allelic variant is associated with resistance to PD-1-targeted immunotherapy in patients with non-small cell lung cancer. 30765392
2019-11-02 10:32:00 The higher frequencies of KIR3DS1-Bw4 and homozygotic KIR2DS4- in patients compared with controls suggest they confer susceptibility to polycystic ovary syndrome. A lower frequency of KIR2DS4-full was observed in patients. 30099219
2019-06-01 10:28:00 Blocking the interaction of HLA-F on HLA-null cell line 721.221 with KIR3DS1-Fc chimeric protein or anti-HLA-F antibodies on exclusively gated KIR3DS1(+) cells reduced the frequency of functional cells compared with that of unblocked conditions for stimulated KIR3DS1(+) natural killer cells. Thus, ligation of KIR3DS1 activates primary natural killer cells for several antiviral functions. 29743316
2019-03-30 12:22:00 Data show that allelic diversity of killer cell immunoglobulin-like receptors KIR3DL1/S1 was similar in Mexican Mestizos from Mexico and in Hispanics from USA. 30365992

名称对应

Type IDs
Synonymous CD158E2, KIR-123FM, KIR-G1, NKAT-10, NKAT10
Gene
UniProtKB-ID: KI3S1_HUMAN, Q4KN23_HUMAN, O43469_HUMAN, Q99565_HUMAN, A0A0G2JN05_HUMAN
UniprotKB: Q14943, Q4KN23, O43469, Q99565, A0A0G2JN05
UniParc: UPI00000716CB, UPI000055208F, UPI0000070B25, UPI000006FD19, UPI000165DD0B
EMBL: MN167519, BC098107, CU459006, AY760055, KP420440, X97232, KU645196, L76661, GU182347, MN167518, AY760056, JX008028, GU182339, MN167504, BC098288, AY760033, GU182359, GU182355, MN167515, MN167525, EU156175, AL133414, AF022044, MN167506, GU182352, KU645197, AY760032, JX008031
Ensembl: ENSG00000275037, ENSG00000275434, ENSG00000283719, ENSG00000276534, ENSG00000275608, ENSG00000284301, ENSG00000274283, ENSG00000276498, ENSG00000274465, ENSG00000284111, ENSG00000283889
KO: hsa:3813
Nucleutide sequences
EMBL-CDS: AAB36589.1, AAV32446.1, AFV74772.1, AAH98107.1, AAB95317.1, AAH98288.1, QKY12371.1, QKY12200.1, AAX89527.1, QKY12283.1, AFV74754.1, AAV32445.1, QKY12319.1, QKY12307.1, ABX88986.1, AAX89526.1, QKY12216.1, CAA65871.1
Ensembl_TRS: ENST00000616388, ENST00000614217, ENST00000639068, ENST00000640837, ENST00000642723, ENST00000640367, ENST00000645127, ENST00000645932, ENST00000611309, ENST00000646460, ENST00000638235, ENST00000644102, ENST00000640772, ENST00000647019, ENST00000639016, ENST00000621178, ENST00000620926, ENST00000614429, ENST00000640919, ENST00000644389, ENST00000620498, ENST00000640177, ENST00000618890, ENST00000610716, ENST00000646860, ENST00000642472, ENST00000639497, ENST00000620731, ENST00000643091, ENST00000639892, ENST00000639696, ENST00000645896, ENST00000638609, ENST00000642388
Protein sequencees
Ensembl_PRO: ENSP00000481772, ENSP00000480199, ENSP00000494803, ENSP00000493547, ENSP00000494777, ENSP00000491813, ENSP00000491041, ENSP00000477663, ENSP00000491935, ENSP00000492214, ENSP00000494006, ENSP00000494270, ENSP00000494812, ENSP00000491829, ENSP00000482507, ENSP00000493624, ENSP00000477819, ENSP00000496090, ENSP00000492553, ENSP00000480225, ENSP00000478122, ENSP00000482441, ENSP00000492575, ENSP00000484872, ENSP00000492717, ENSP00000494356, ENSP00000491787, ENSP00000480346, ENSP00000491446, ENSP00000496009, ENSP00000494005, ENSP00000492490, ENSP00000492735, ENSP00000494548
RefSeq: NP_001269100.1, NP_001077008.1, NP_001269099.1
Others
UniRef100: UniRef100_Q14943, UniRef100_O43469, UniRef100_A0A0G2JN05, UniRef100_Q99565, UniRef100_Q4KN23
UniRef90: UniRef90_P43629, UniRef90_P43629-2, UniRef90_Q4KN23
UniRef50: UniRef50_P43628, UniRef50_P43629, UniRef50_Q99706-5
UniGene: Hs.743496

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