| Type | Description |
|---|---|
| Definition | inturned planar cell polarity protein |
| Date | Results | Publications |
|---|---|---|
| 2018-12-22 11:54:00 | propose a role for Intu in protecting cells and tissues after injury by targeting for degradation and maintaining primary cilia | 29581513 |
| 2016-02-20 11:48:00 | Mice with a recessive hypomorphic Intu missense mutation affecting a conserved hydrophobic residue (I813N) near the C-terminus display polydactyly, retarded growth, skeletal defects, reduced survival, and a moderate loss of cilia. | 25774014 |
| 2013-08-31 11:12:00 | Targeting Intu in the epidermis resulted in almost complete loss of primary cilia in epidermal and follicular keratinocytes, and a suppressed hedgehog signaling pathway. | 22935613 |
| 2011-12-10 10:26:00 | Data show that the functions of both Inturned and Fuzzy in neural tube patterning are dependent on the presence of cilia. | 21761479 |
| Type | IDs |
|---|---|
| Synonymous | 9230116I04Rik, 9430087H23Rik, Pdzd6, Pdzk6, mKIAA1284 |
| Gene |
UniProtKB-ID:
INTU_MOUSE
UniprotKB:
Q059U7
UniParc:
UPI00000E96C7,
UPI0000565A2B
EMBL:
BC132387,
AK035092,
BC125523,
CH466530,
AK040233,
AK122485,
AC146980,
AC163023
Ensembl:
ENSMUSG00000060798,
ENSMUSG00000116357
KO:
mmu:380614
|
| Nucleutide sequences |
EMBL-CDS:
BAC28943.1,
BAC30547.1,
AAI25524.1,
BAC65767.1,
AAI32388.1,
EDL35133.1
Ensembl_TRS:
ENSMUST00000061590,
ENSMUST00000230501,
ENSMUST00000091186,
ENSMUST00000230028
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000155476,
ENSMUSP00000155551,
ENSMUSP00000054313,
ENSMUSP00000088725
RefSeq:
NP_780724.3,
XP_036019038.1,
XP_017175116.1,
XP_017175117.1,
XP_030108519.1
|
| Others |
UniRef100:
UniRef100_Q059U7
UniRef90:
UniRef90_Q059U7
UniRef50:
UniRef50_Q059U7
UniGene:
Mm.105309,
Mm.432345
CCDS:
CCDS84619.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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