| Type | Description |
|---|---|
| Definition | protein tyrosine phosphatase receptor type Q |
| Date | Results | Publications |
|---|---|---|
| 2020-09-26 13:04:00 | First confirmatory study on as an autosomal dominant non-syndromic hearing loss gene. | 31655630 |
| 2018-12-01 12:11:00 | The studies findings suggest that the novel compound heterozygous mutations, c.4472C>T (p.T1491M) and c.1973T>C (p.V658A), are the cause of congenital Sensorineural Hearing Loss in a Chinese family. | 29849575 |
| 2018-10-20 12:21:00 | We identified a heterozygous nonsense mutation, c.6881G>A (p.Trp2294*), in the last coding exon of has been linked with recessive (DFNB84A), but not dominant deafness. protein would lack only six terminal residues and could exert a dominant-negative effect | 29309402 |
| 2018-04-21 11:29:00 | may be a useful biomarker for discriminating between patients with Idiopathic normal pressure hydrocephalus and Alzheimer's disease. | 28714010 |
| 2016-07-16 11:26:00 | Confirm contribution of PTPRZ1, and especially in CRC carcinogenesis and demonstrated that expression is correlated with KRAS mutation. | 26851024 |
| Type | IDs |
|---|---|
| Synonymous | DFNA73, DFNB84, DFNB84A, PTPGMC1, R-PTP-Q |
| Gene |
UniProtKB-ID:
A0A087WZU1_HUMAN
UniprotKB:
A0A087WZU1
UniParc:
UPI000192953C
EMBL:
AC083812,
ABBA01053496,
AC074031
Ensembl:
ENSG00000139304
KO:
hsa:374462
|
| Nucleutide sequences |
Ensembl_TRS:
ENST00000644991
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000495607
RefSeq:
NP_001138498.1,
XP_016874762.1,
XP_016874763.1,
XP_016874764.1
|
| Others |
UniRef100:
UniRef100_A0A087WZU1
UniRef90:
UniRef90_Q9UMZ3
UniRef50:
UniRef50_Q9UMZ3
UniGene:
Hs.539284
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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