| Type | Description |
|---|---|
| Definition | amyloid beta (A4) precursor protein |
| Date | Results | Publications |
|---|---|---|
| 2012-08-25 10:20:00 | Reduction in ChAT activity instigated by AbetaOs may thus be a relevant event in early stage AD pathology, preceding the loss of cholinergic neurons commonly observed in AD brains. | 22505713 |
| 2011-07-23 10:53:00 | Results compare the effect of secretase inhibitors and modulators on Abeta formation in primary chicken telencephalic neurons and in a human neuroglioma cell line (H4) ectopically expressing human APP with the Swedish double mutation. | 20603724 |
| 2010-01-21 00:00:00 | A "CAGA" sequence proximal to the "ATG" start codon & immediately upstream of an interleukin-1-responsive element was found in a location unique to APP genes of amyloid plaque-forming species & absent in all other genes surveyed. | 15208260 |
| 2010-01-21 00:00:00 | fibrils caused extensive aggregation of human erythrocytes and lipid vesicles without any significant lysis | 19322639 |
| Type | IDs |
|---|---|
| Gene |
UniProtKB-ID:
Q9DGJ7_CHICK,
F1P0B2_CHICK
UniprotKB:
Q9DGJ7,
F1P0B2
UniParc:
UPI00000FD2FE,
UPI000739AB75
EMBL:
AADN05000690,
AF289219
Ensembl:
ENSGALG00000015770
KO:
gga:374198
|
| Nucleutide sequences |
EMBL-CDS:
AAG00594.1
Ensembl_TRS:
ENSGALT00000001896
|
| Protein sequencees |
Ensembl_PRO:
ENSGALP00000001894
RefSeq:
XP_015154580.1,
NP_989639.1
|
| Others |
UniRef100:
UniRef100_Q9DGJ7,
UniRef100_F1P0B2
UniRef90:
UniRef90_P05067-4,
UniRef90_P05067-8
UniRef50:
UniRef50_P05067
UniGene:
Gga.4613
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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