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373156 GSTK1

373156

GSTK1

glutathione S-transferase kappa 1

protein-coding

Homo sapiens

基因描述

Type Description
Definition glutathione S-transferase kappa 1

研究结论

Date Results Publications
2020-12-05 13:03:00 The DsbA-L gene is associated with respiratory function of the elderly via its adiponectin multimeric or antioxidant properties. 32249844
2020-10-10 13:03:00 DsbA-L mediated renal tubulointerstitial fibrosis in UUO mice. 32948751
2020-07-25 10:27:00 DsbA-L modifies mitochondrial fission, linking alterations in mitochondrial dynamics during tubular injury in the pathogenesis of diabetic kidney disease. 32167139
2020-02-15 13:04:00 DsbA-L plays a critical protective role in renal ectopic fat deposition and lipid-related kidney injury in mice with diabetic nephropathy (DN) and patients with DN. The mechanisms might involve the inhibition of cholesterol synthesis through the inactivation of HMGCR and the promotion of lipolysis through the activation of ATGL and the subsequent reduction of lipid droplets accumulation in the kidney. 30791996
2019-09-28 10:04:00 The population prediction model of BMI indicated that the DsbA-L T/T genotype was significantly associated with a high BMI. The BMI-based NAFLD prediction model showed that the DsbA-L T/T genotype did not have any direct impact on the risk of NAFLD, whereas the structural equation model suggested that this genotype might be indirectly or partially associated with NAFLD risk through a high BMI and low adiponectin. 29569850

名称对应

Type IDs
Synonymous GST, GST 13-13, GST13, GST13-13, GSTK1-1, hGSTK1
Gene
UniProtKB-ID: GSTK1_HUMAN, Q6FII1_HUMAN
UniprotKB: Q9Y2Q3, Q6FII1
UniParc: UPI000022839D, UPI0000D6CC58, UPI0000D6CC68, UPI000013C81A
EMBL: AK289570, AY520571, BC050715, AF087849, CR533445, AL136938, CH471198, AK289580, AF068287, AK299968, AY486465, AK295592, AF070657, CH236959, BC001231, BC063425, AC073342
Ensembl: ENSG00000197448
KO: hsa:373156
Nucleutide sequences
EMBL-CDS: AAF65506.1, AAH63425.1, AAH01231.1, AAH50715.1, AAS00610.1, AAD20963.1, EAW51877.1, CAB66872.1, BAF82259.1, BAG58483.1, BAG61794.1, AAP97160.1, AAS01180.1, EAW51880.1, CAG38476.1, EAL23783.1, BAF82269.1
Gene_ORFName: HDCMD47P, hCG_20682, tcag7.883
Ensembl_TRS: ENST00000358406, ENST00000443571, ENST00000479303, ENST00000409500
Protein sequencees
Ensembl_PRO: ENSP00000415813, ENSP00000431049, ENSP00000386944, ENSP00000351181
RefSeq: NP_001137151.1, NP_057001.1, NP_001137152.1, NP_001137153.1
Others
UniRef100: UniRef100_Q9Y2Q3
UniRef90: UniRef90_Q9Y2Q3
UniRef50: UniRef50_Q9Y2Q3
UniGene: Hs.390667
CCDS: CCDS5877.1, CCDS47731.1, CCDS47732.1, CCDS47730.1

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