| Type | Description |
|---|---|
| Definition | Heat shock factor |
| Date | Results | Publications |
|---|---|---|
| 2018-02-24 11:37:00 | Azadiradione ameliorates polyglutamine expansion disease in Drosophila by potentiating DNA binding activity of heat shock factor 1. | 27835876 |
| 2017-09-02 13:46:00 | HSF role in the heat shock response to viral infection | 26234525 |
| 2017-07-29 10:37:00 | Knockdown of the Drosophila Nrf1 and Nrf2 ortholog cap 'n' collar isoform-C, but not Hsf1, blocks the protective effect of ASC-JM17 on mutant AR-induced eye degeneration in flies. Our observations indicate that activation of the Nrf1/Nrf2 pathway is a viable option for pharmacological intervention in SBMA and potentially other polyglutamine diseases. | 26962150 |
| 2017-05-20 14:24:00 | HSF is dispensable for establishing or maintaining Pol II pausing but is critical for the release of paused Pol II into the gene body at a subset of highly activated genes | 27492368 |
| 2016-02-20 11:29:00 | The survival curves of heterozygotes on hsf-1 and hsf-4 alleles are similar in spite of HSF-4 protein is slightly active on normal temperature. | 26856085 |
| Type | IDs |
|---|---|
| Synonymous | CG5748, D-HSF, Dm-Hsf, DmHSF, DmHSFa, Dmel\CG5748, HSF, HSF1, HSFa, Hsf1, dHSF, dHSFa, heat shock factor, hsf, l(2)03091 |
| Gene |
UniProtKB-ID:
HSF_DROME,
Q4H2F9_DROME,
Q4H2F8_DROME,
Q4H2F7_DROME
UniprotKB:
P22813,
Q4H2F9,
Q4H2F8,
Q4H2F7
UniParc:
UPI000056D0CC,
UPI000056D0CD,
UPI000056D0CE,
UPI0000124896
EMBL:
AB211169,
AE013599,
AB211170,
M60070,
AB211168
EnsemblGenome:
FBgn0001222
KO:
dme:Dmel_CG5748
|
| Nucleutide sequences |
EMBL-CDS:
AAF57749.1,
AAA28642.1,
BAE16321.1,
ABI31104.1,
ABI31103.1,
BAE16322.1,
BAE16323.1,
ABI31102.1
Gene_ORFName:
CG5748,
Dmel_CG5748,
CG5748,
CG5748,
Dmel_CG5748,
Dmel_CG5748,
CG5748
EnsemblGenome_TRS:
FBtr0086782,
FBtr0110964,
FBtr0110965,
FBtr0110966
|
| Protein sequencees |
EnsemblGenome_PRO:
FBpp0085961,
FBpp0110264,
FBpp0110265,
FBpp0110266
RefSeq:
NP_001036556.1,
NP_476575.1,
NP_001036557.1,
NP_001036555.1
|
| Others |
UniRef100:
UniRef100_Q4H2F9,
UniRef100_P22813,
UniRef100_Q4H2F8,
UniRef100_Q4H2F7
UniRef90:
UniRef90_P22813
UniRef50:
UniRef50_P22813
UniGene:
Dm.4107
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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