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[VARIOUS ALLELES OF HSF HEAT-SHOCK TRANSCRIPTION FACTOR OF DROSOPHILA MELANOGASTER INCREASE VIABILITY OF ITS CARRIERS IN UNFAVORABLE ENVIRONMENTS].

Adv Gerontol. 2015;28(2):248-56
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摘要

We found increased viability in heterozygous carriers of hsf heat shock transcription factor n comparison with wild type. The effect depends on temperature, sex and direction of crosses. Viability effect is more evident in conditions of soft temperature stress. The males are more sensitive. The maternal effect is observed: if hsf*allele came from mother, the viability effect is stronger. The survival curves of heterozygotes on hsf-1 and hsf-4 alleles are similar in spite of HSF-4 protein is slightly active on normal temperature.

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