| Type | Description |
|---|---|
| Definition | immunoglobulin superfamily containing leucine rich repeat |
| Date | Results | Publications |
|---|---|---|
| 2020-12-12 13:28:00 | Secreted stromal protein ISLR promotes intestinal regeneration by suppressing epithelial Hippo signaling. | 32128839 |
| 2020-06-06 11:30:00 | Meflin is expressed by pancreatic stellate cells that are a source of cancer-associated fibroblasts in pancreatic ductal adenocarcinoma. Delivery of a Meflin-expressing lentivirus into the tumor stroma or overexpression of Meflin in CAFs suppressed the growth of xenograft tumors. Meflin deficiency or low expression resulted in straightened stromal collagen fibers, a signature for aggressive tumors, in human PDAC tissues. | 31439548 |
| Type | IDs |
|---|---|
| Synonymous | HsT17563, Meflin |
| Gene |
UniProtKB-ID:
ISLR_HUMAN,
A0A146E5L3_HUMAN
UniprotKB:
O14498,
A0A146E5L3
UniParc:
UPI0000049E09
EMBL:
BR001380,
AY358871,
AB024537,
AB003184,
AB024536
Ensembl:
ENSG00000129009,
ENSG00000288508
KO:
hsa:3671
|
| Nucleutide sequences |
EMBL-CDS:
BAA85971.1,
BAA85970.1,
AAQ89230.1,
BAA22848.1,
FAA01192.1
Gene_ORFName:
UNQ189/PRO215
Ensembl_TRS:
ENST00000672683,
ENST00000395118,
ENST00000249842,
ENST00000671810
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000378550,
ENSP00000499984,
ENSP00000500029,
ENSP00000249842
RefSeq:
NP_005536.1,
NP_958934.1
|
| Others |
UniRef100:
UniRef100_O14498
UniRef90:
UniRef90_O14498
UniRef50:
UniRef50_O14498
UniGene:
Hs.699822,
Hs.745166
CCDS:
CCDS10260.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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