| Type | Description |
|---|---|
| Definition | Activity-regulated cytoskeleton associated protein 1 |
| Date | Results | Publications |
|---|---|---|
| 2020-09-19 16:26:00 | Structure of Drosophila melanogaster ARC1 reveals a repurposed molecule with characteristics of retroviral Gag. | 31911950 |
| 2020-09-12 16:06:00 | A Drosophila model of Pontocerebellar Hypoplasia reveals a critical role for the RNA exosome in neurons. | 32645003 |
| 2020-04-18 12:34:00 | We report high-resolution structures of retrovirus-like capsids formed by Drosophila dArc1 and dArc2 that have surface spikes and putative internal RNA-binding domains | 31907439 |
| 2019-01-05 11:32:00 | Arc1 protein forms capsid-like structures that bind darc1 mRNA in neurons and is loaded into extracellular vesicles that are transferred from motorneurons to muscles. | 29328915 |
| 2017-11-11 12:34:00 | trr and G9a also have common direct targets, including the Drosophila ortholog of Arc (Arc1), a key regulator of synaptic plasticity. Our data highlight the clinical and molecular convergence between the KMT2 and EHMT protein families, which may contribute to a molecular network underlying a larger group of intellectual disability / autism spectrum disorder -related disorders. | 29069077 |
| Type | IDs |
|---|---|
| Synonymous | Arc, CG12505, Dmel\CG12505, anon-WO0153538.31, anon-WO0153538.40, anon-WO0153538.41, anon-WO0153538.43, anon-WO0153538.45, arc1, dARC1, dArc1 |
| Gene |
UniProtKB-ID:
ARC1_DROME
UniprotKB:
Q7K1U0
UniParc:
UPI000007A04E
EMBL:
AE013599,
AY061464
EnsemblGenome:
FBgn0033926
KO:
dme:Dmel_CG12505
|
| Nucleutide sequences |
EMBL-CDS:
AAL29012.1,
AAF58256.1
Gene_ORFName:
CG12505
EnsemblGenome_TRS:
FBtr0087560
|
| Protein sequencees |
EnsemblGenome_PRO:
FBpp0086687
RefSeq:
NP_610955.1
|
| Others |
UniRef100:
UniRef100_Q7K1U0
UniRef90:
UniRef90_Q7K1U0
UniRef50:
UniRef50_Q7K1U0
UniGene:
Dm.6973
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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