Xrcc5 - X-ray repair cross complementing 5-BMKCloudï½ç¾è¿å®¢äº

例如："NBL1", "4681", "drought"

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363247 Xrcc5

基因描述

Type	Description
Definition	X-ray repair cross complementing 5

研究结论

Date	Results	Publications
2016-06-28 11:32:00	The radiosensitizing effect of beclin-1 knockdown may result from the disruption of nuclear translocation and DNA binding activity of Ku proteins and consequent attenuation of double strand break repair.	26321753
2010-01-21 00:00:00	Sp1, Sp2 and Sp4 transcription factors play a role in activating cholesterol desmolase gene transcription in the nervous system, and Ku antigen may further augment this activation	14576192

名称对应

Type	IDs
Synonymous	Ku80, Kup80
Gene	UniProtKB-ID: Q6P7P8_RAT UniprotKB: Q6P7P8 UniParc: UPI0000213452 EMBL: BC061576 KO: rno:363247
Nucleutide sequences	EMBL-CDS: AAH61576.1
Protein sequencees	RefSeq: NP_803154.1
Others	UniRef100: UniRef100_Q6P7P8 UniRef90: UniRef90_P27641 UniRef50: UniRef50_P27641 UniGene: Rn.52078

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mRNA

Protein

UniprotKB

Description

Refseq

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Location

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Pubmed编号	文献信息	发表日期	相关基因
32103174	DNA-PKcs has KU-dependent function in rRNA processing and haematopoiesis. Nature Zhengping Shao , Ryan A Flynn , Jennifer L Crowe , Yimeng Zhu , Jialiang Liang , Wenxia Jiang , Fardin Aryan , Patrick Aoude , Carolyn R Bertozzi , Verna M Estes , Brian J Lee , Govind Bhagat , Shan Zha , Eliezer Calo	2020-03-01	-
28712728	HEXIM1 and NEAT1 Long Non-coding RNA Form a Multi-subunit Complex that Regulates DNA-Mediated Innate Immune Response. Mol Cell Mehdi Morchikh , Alexandra Cribier , Raoul Raffel , Sonia Amraoui , Julien Cau , Dany Severac , Emeric Dubois , Olivier Schwartz , Yamina Bennasser , Monsef Benkirane	2017-08-03	-
27248496	WDR76 Co-Localizes with Heterochromatin Related Proteins and Rapidly Responds to DNA Damage. PLoS ONE Joshua M Gilmore , Mihaela E Sardiu , Brad D Groppe , Janet L Thornton , Xingyu Liu , Gerald Dayebgadoh , Charles A Banks , Brian D Slaughter , Jay R Unruh , Jerry L Workman , Laurence Florens , Michael P Washburn	2016-01-01	-
26359349	Heat shock factor 1, an inhibitor of non-homologous end joining repair. Oncotarget Ga-Young Kang , Eun-Ho Kim , Hae-June Lee , Na-Yeon Gil , Hyuk-Jin Cha , Yun-Sil Lee	2015-10-06	-
25941166	XLS (c9orf142) is a new component of mammalian DNA double-stranded break repair. Cell Death Differ. A Craxton , J Somers , D Munnur , R Jukes-Jones , K Cain , M Malewicz	2015-06-01	-
25852083	DNA-dependent protein kinase (DNA-PK) permits vascular smooth muscle cell proliferation through phosphorylation of the orphan nuclear receptor NOR1. Cardiovasc. Res. Senad Medunjanin , Jan-Marcus Daniel , SÃ¶nke Weinert , Jochen Dutzmann , Frank Burgbacher , Sarah Brecht , Dennis Bruemmer , Thilo KÃ¤hne , Michael Naumann , Daniel G Sedding , Werner Zuschratter , Ruediger C Braun-Dullaeus	2015-06-01	XRCC6, PRKDC, XRCC5, NR4A3
26321753	Blockage of Autophagy in C6 Glioma Cells Enhanced Radiosensitivity Possibly by Attenuating DNA-PK-Dependent DSB Due to Limited Ku Nuclear Translocation and DNA Binding. Curr. Mol. Med. C Liu , W He , M Jin , H Li , H Xu , H Liu , K Yang , T Zhang , G Wu , J Ren	2015-01-01	-
24095731	TRF2 interaction with Ku heterotetramerization interface gives insight into c-NHEJ prevention at human telomeres. Cell Rep Albert Ribes-Zamora , Sandra M Indiviglio , Ivana Mihalek , Christopher L Williams , Alison A Bertuch	2013-10-17	XRCC6, TERF2IP, TERF1, TERF2, XRCC4, XRCC5, NHEJ1
22658674	Insights into RNA biology from an atlas of mammalian mRNA-binding proteins. Cell Alfredo Castello , Bernd Fischer , Katrin Eichelbaum , Rastislav Horos , Benedikt M Beckmann , Claudia Strein , Norman E Davey , David T Humphreys , Thomas Preiss , Lars M Steinmetz , Jeroen Krijgsveld , Matthias W Hentze	2012-06-08	GNPDA1, SCARNA27, GABPB1-AS1, NFYC-AS1, FKSG29, PHKA2-AS1, HDAC6, PDCD6, C17orf96, LOC100287042, MIR3652, ARPC4-TTLL3, ATP5J2-PTCD1, TGIF2-C20orf24, FARSB, ABCC5, ABCF2, HUWE1, ARPC4, ARPC1B, ACTR3, ACTR1A, LRPPRC, TRAP1, BCAP31, NAMPT, RBM12, TOB1, G3BP1, SUGP2, MBNL2, ABI2, CEBPZ, ATP6AP2, SLC25A15, RCL1, RBM7, RBM6, RBM5, ALYREF, PSME3, MPHOSPH10, NUTF2, USPL1, DDX39A, STX6, HNRNPR, MRPS31, RIDA, SF3B4, AKAP8, STUB1, SIGMAR1, SMNDC1, BCAS2, SF3A1, CDKN2A, APBB3, SMYD5, ADAR, EMC8, NPM3, HMG20A, NOD1, RACK1, NDC80, NSA2, YAP1, CD2BP2, TUBGCP3, RBM14, EMG1, ACAA2, PPIE, TAB1, MAD2L2, PIBF1, SLC25A17, NXF1, CREB3, LRRC41, SYNCRIP, ENOX2, MYBBP1A, DDX17, ADARB2, CHERP, HYOU1, IPO8, NOP56, RNASEH2A, GLRX3, DCTN2, LAMTOR5, PRDX4, AGPAT1, RPP30, SLU7, MRPL28
22681889	The mRNA-bound proteome and its global occupancy profile on protein-coding transcripts. Mol. Cell Alexander G Baltz , Mathias Munschauer , BjÃ¶rn SchwanhÃ¤usser , Alexandra Vasile , Yasuhiro Murakawa , Markus Schueler , Noah Youngs , Duncan Penfold-Brown , Kevin Drew , Miha Milek , Emanuel Wyler , Richard Bonneau , Matthias Selbach , Christoph Dieterich , Markus Landthaler	2012-06-08	NBPF10, TSFM, LRPPRC, RBM12, G3BP1, SUGP2, MBNL2, CEBPZ, TRIM28, RBM7, RBM6, RBM5, ALYREF, MPHOSPH10, EIF1, DDX39A, HNRNPR, MRPS31, POP7, SRRM1, SF3B4, AKAP8, LOC400927-CSNK1E, SAP18, EIF1B, SF3A1, CDKN2A, ADAR, NPM3, RACK1, NSA2, ADARB1, RBM14, EMG1, NXF1, SYNCRIP, MYBBP1A, DDX17, CHERP, NOP56, PRPF8, IGF2BP1, IGF2BP3, IGF2BP2, KHDRBS3, KHDRBS1, CELF1, CELF2, KIF1C, SRSF10, UTP14A, CPSF4, TCERG1, RNPS1, SUB1, SRSF8, SF3A3, HNRNPA0, EBNA1BP2, CKAP4, ASCC3, GCN1, SF3B2, NUDT21, CPSF6, DDX52, CHD2, DUSP14, DIDO1, NUPL2, HNRNPUL1, KRR1, LSM6, PSIP1, STRAP, SUPT16H, MRPL3, ATXN2L, LARP4, DDX42, PDAP1, U2AF2, WBSCR22, KCTD12, CIRBP, MRPL54, FTSJ3, EXOSC6, CHCHD1, CLK3, CLTC, HIST4H4, ZC3H18, MSI2, MRPL10, RAVER1, C1orf131, RBM45, CPEB2

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