INPP1 - inositol polyphosphate-1-phosphatase-BMKCloudï½ç¾è¿å®¢äº

例如："NBL1", "4681", "drought"

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3628 INPP1

基因描述

Type	Description
Definition	inositol polyphosphate-1-phosphatase

研究结论

Date	Results	Publications
2020-09-12 16:04:00	INPP1 up-regulation by miR-27a contributes to the growth, migration and invasion of human cervical cancer.	31557403
2018-11-10 12:02:00	We found the suicide-associated gene coexpression network. The reconstructed network consisted of 104 genes. Topological analysis showed that in total, CCK, INPP1, DDC, and NPY genes are the most fundamental hubs in the network	29381655
2015-08-29 10:41:00	High INPP1 expression is associated with cancer aggressiveness.	24738946
2014-06-21 11:07:00	results suggest that genetic variability at rs669838-IMPA2,rs4853694-INPP1, rs1732170-GSK3b and rs11921360-GSK3b genes is associated with a higher risk of attempting suicide in bipolar patients.	23453640
2010-01-21 00:00:00	association study performed between the 5' regulatory region of the serotonin transporter gene (5-HTTLPR), the inositol polyphosphate 1-phosphatase gene (INPP1) and bipolar disorder using our sample of proband/parent trios	11901356

名称对应

Type	IDs
Gene	UniProtKB-ID: INPP_HUMAN, Q6IBG4_HUMAN UniprotKB: P49441, Q6IBG4 UniParc: UPI000012D697 EMBL: CR541707, CR456840, CH471058, BC106006, AC092178, BC015496, L08488, AF141325, KU178146 Ensembl: ENSG00000151689 KO: hsa:3628
Nucleutide sequences	EMBL-CDS: AAD46766.1, AAH15496.1, AAA36117.1, ALQ33604.1, CAG33121.1, CAG46508.1, AAI06007.1, EAX10872.1, EAX10869.1, AAY24179.1, EAX10871.1 Gene_ORFName: hCG_24794 Ensembl_TRS: ENST00000392329, ENST00000322522
Protein sequencees	Ensembl_PRO: ENSP00000376142, ENSP00000325423 RefSeq: NP_001122400.1, XP_024308643.1, XP_005246589.1, NP_002185.1
Others	UniRef100: UniRef100_P49441 UniRef90: UniRef90_P49441 UniRef50: UniRef50_P49441 UniGene: Hs.32309 CCDS: CCDS2305.1

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mRNA

Protein

UniprotKB

Description

Refseq

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Pubmed编号	文献信息	发表日期	相关基因
31557403	INPP1 up-regulation by miR-27a contributes to the growth, migration and invasion of human cervical cancer. J Cell Mol Med Pu Li , Qiaoge Zhang , Hua Tang	2019-11-01	-
30652415	Oncogenic functions of protein kinase D2 and D3 in regulating multiple cancer-related pathways in breast cancer. Cancer Med Yan Liu , Jian Li , Zhifang Ma , Jun Zhang , Yuzhi Wang , Zhenghong Yu , Xue Lin , Zhi Xu , Qian Su , Li An , Yehui Zhou , Xinxing Ma , Yiwen Yang , Feifei Wang , Qingfei Chen , Yunchao Zhang , Jilinlin Wang , Huilin Zheng , Aihua Shi , Shuang Yu , Jingzhong Zhang , Weiyong Zhao , Liming Chen	2019-02-01	-
29381655	Integrated analysis of the genetic basis of suicidal behavior: what has been shown by structural genetic studies so far. Psychiatr. Genet. Ali Bozorgmehr , Mohammad Ghadirivasfi , Mostafa Tavakoli , Hamid Rahmani , Fahimeh Heydari , Esmaeil Shahsavand Ananloo	2018-04-01	-
29791485	Alterations in the brain interactome of the intrinsically disordered N-terminal domain of the cellular prion protein (PrPC) in Alzheimer's disease. PLoS ONE Sarah Ulbrich , Petra Janning , Ralf Seidel , Jakob Matschke , Anika Gonsberg , Sebastian Jung , Markus Glatzel , Martin Engelhard , Konstanze F Winklhofer , JÃ¶rg Tatzelt	2018-01-01	-
28319085	Synergistic drug combinations for cancer identified in a CRISPR screen for pairwise genetic interactions. Nat. Biotechnol. Kyuho Han , Edwin E Jeng , Gaelen T Hess , David W Morgens , Amy Li , Michael C Bassik	2017-05-01	-
26871637	Widespread Expansion of Protein Interaction Capabilities by Alternative Splicing. Cell Xinping Yang , Jasmin Coulombe-Huntington , Shuli Kang , Gloria M Sheynkman , Tong Hao , Aaron Richardson , Song Sun , Fan Yang , Yun A Shen , Ryan R Murray , Kerstin Spirohn , Bridget E Begg , Miquel Duran-Frigola , Andrew MacWilliams , Samuel J Pevzner , Quan Zhong , Shelly A Trigg , Stanley Tam , Lila Ghamsari , Nidhi Sahni , Song Yi , Maria D Rodriguez , Dawit Balcha , Guihong Tan , Michael Costanzo , Brenda Andrews , Charles Boone , Xianghong J Zhou , Kourosh Salehi-Ashtiani , Benoit Charloteaux , Alyce A Chen , Michael A Calderwood , Patrick Aloy , Frederick P Roth , David E Hill , Lilia M Iakoucheva , Yu Xia , Marc Vidal	2016-02-11	USH1C, PQBP1, OPTN, RBM5, CDK5, CDK7, RABEPK, SRRM1, NOD1, CD2BP2, RBM14, HAX1, SLC30A9, STK25, SEMA4F, SLC19A2, CETP, SRSF10, SEPT9, ALDH1L1, RCC1, LDB3, AKAP10, SEC63, PHF21B, HELQ, CKB, ERCC8, CLCN2, ZFYVE27, CLPTM1, TTC8, C15orf40, COL1A2, BBS5, ACMSD, DNAJC19, CPA2, C7orf34, CRH, CRK, RDH12, MIPOL1, ZNF688, SLC25A10, NKX2-5, CTNS, CTSD, UPP2, CYBB, CYP11A1, TSTD2, DAO, REM2, DYX1C1, DCN, DDC, GLIS3, DGUOK, DHCR7, DMD, E2F6, TYMP, EGR2, FLCN, EPHX1, EYA4, ETFA, ETV6, FANCC, FANCG, EFEMP1, MICU2, ZUFSP, FCGR3A, ABCB7, FGA, FGFR1, FH, DOLK, KIAA0907, ARHGEF15, SETX, ARHGAP26, SPG20, FMO3, ETHE1, SLC39A14, CDK20, SMUG1, FXN, FTSJ1, MCM9, GABRA2, GAD1, SUMF2, GALT, UNC50, FBXO8
24738946	Inositol phosphate recycling regulates glycolytic and lipid metabolism that drives cancer aggressiveness. ACS Chem. Biol. Daniel I Benjamin , Sharon M Louie , Melinda M Mulvihill , Rebecca A Kohnz , Daniel S Li , Lauryn G Chan , Antonio Sorrentino , Sourav Bandyopadhyay , Alyssa Cozzo , Anayo Ohiri , Andrei Goga , Shu-Wing Ng , Daniel K Nomura	2014-06-20	INPP1
24722188	Protein interaction network of alternatively spliced isoforms from brain links genetic risk factors for autism. Nat Commun Roser Corominas , Xinping Yang , Guan Ning Lin , Shuli Kang , Yun Shen , Lila Ghamsari , Martin Broly , Maria Rodriguez , Stanley Tam , Shelly A Trigg , Changyu Fan , Song Yi , Murat Tasan , Irma Lemmens , Xingyan Kuang , Nan Zhao , Dheeraj Malhotra , Jacob J Michaelson , Vladimir Vacic , Michael A Calderwood , Frederick P Roth , Jan Tavernier , Steve Horvath , Kourosh Salehi-Ashtiani , Dmitry Korkin , Jonathan Sebat , David E Hill , Tong Hao , Marc Vidal , Lilia M Iakoucheva	2014-01-01	ADA, CDH9, CDH10, TRIM10, SORBS3, PSME3, CALCOCO2, SPRY2, EFS, IKZF1, CDR2, NDC80, TACC3, CDX4, ZBTB18, NEBL, SPAG5, RBCK1, RAI2, VAMP5, CPLX1, RCBTB2, RBPMS, MID2, RAPGEF4, KLF12, EXOSC8, DTX2, GALNT13, GPRASP2, CMTM5, AGAP1, RAB3IP, SSX2IP, PIH1D2, RHEBL1, PRR20A, FSD2, ADORA2A, FUNDC1, PTCHD1, CRMP1, CRX, NOL4L, DYDC1, MIPOL1, MGAT5B, CTBP1, CTBP2, TTC23L, ADRB2, AMOT, ADSL, SAXO1, CCDC67, DAB1, DAO, OTUD7A, MARCH10, AP2B1, AES, TXLNB, FAM9B, DHCR7, DHPS, SEPT1, DLG2, DLX1, DLX2, DMPK, DPYD, DPYSL2, DRD3, ABAT, EDA, EIF4E, EIF4EBP1, EIF4EBP2, TXLNA, ERBB2, ESR2, SPERT, REEP3, EEF1AKMT1, RFX6, FGFR3, FHIT, IKZF3, IKZF2, NTNG1, ZBTB1, FAN1, RPIA, SWAP70, SEPT6, CEP68, CYFIP1, GSE1, FAM168A
23453640	Genetic variability at IMPA2, INPP1 and GSK3Î² increases the risk of suicidal behavior in bipolar patients. Eur Neuropsychopharmacol E JimÃ©nez , B Arias , M Mitjans , J M Goikolea , E Roda , P A SÃ¡iz , M P GarcÃa-Portilla , P BurÃ³n , J Bobes , M A Oquendo , E Vieta , A Benabarre	2013-11-01	GSK3B, IMPA2, INPP1
22939629	A census of human soluble protein complexes. Cell Pierre C Havugimana , G Traver Hart , TamÃ¡s Nepusz , Haixuan Yang , Andrei L Turinsky , Zhihua Li , Peggy I Wang , Daniel R Boutz , Vincent Fong , Sadhna Phanse , Mohan Babu , Stephanie A Craig , Pingzhao Hu , Cuihong Wan , James Vlasblom , Vaqaar-un-Nisa Dar , Alexandr Bezginov , Gregory W Clark , Gabriel C Wu , Shoshana J Wodak , Elisabeth R M Tillier , Alberto Paccanaro , Edward M Marcotte , Andrew Emili	2012-08-31	SRB2, TRA1, MED6, CDH2, DDTL, ABI1, SRA1, UQCRFS1P1, SNRPGP15, ZNF316, LOC100132057, PDCD6IP, PDCD6, MED16, PIGK, WASH1, CHAF1A, TOM1L1, HMGXB4, RANBP9, SMC4, UBA2, SAE1, FARSB, ABCB6, ABCF2, TIMM23B, SCAMP3, DPP3, HUWE1, TSSC4, PDCD7, USH1C, PQBP1, ARPC5, ARPC4, ARPC3, ARPC1B, ACTR3, ACTR2, NUBP2, TSFM, PPIF, ARPC2, RAD50, PREB, ACTR1B, ACTR1A, RASGRP1, LRPPRC, PDIA6, TRAP1, RBM12, G3BP1, SUGP2, TRIM28, WASF2, SLC25A13, SORBS3, ALYREF, TXNDC9, CDK4, PRMT3, PSME3, MPHOSPH6, CDK5, NUTF2, EIF1, FLOT1, PSMD14, CDK7, ADAM10, PLIN3, STX6, MSLN, HNRNPR, MRPS31, TIMM17B, RIDA, POP7, SRRM1, CDK9, STAM2, SF3B4, ZMPSTE24, STUB1, UBE4B, BET1, CWC27, SAP18, SMNDC1, BCAS2, EIF1B, SF3A1, MAEA, KATNB1, TCIRG1, RTN3, LANCL1

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