Type | Description |
---|---|
Definition | cutoff |
Date | Results | Publications |
---|---|---|
2017-09-23 13:42:00 | Results confirm that Cutoff is involved in the transcriptional regulation of piRNA clusters and in the repression of transposable elements in germ cells. Surprisingly, however, Cutoff is found enriched at and affects the expression of other noncoding RNAs, including spliceosomal RNAs and small nucleolar RNAs. Finally, mutations in Cutoff result in the deregulation of hundreds of protein-coding genes in germ cells. | 28420675 |
2017-08-26 12:50:00 | Cutoff suppresses RNA polymerase II termination to ensure expression of piRNA precursors. | 27292797 |
2014-08-09 10:27:00 | Analysis of piRNA clusters in the Drosophila ovary shows that hallmarks of II (Pol II) transcription are fundamentally different at uni-strand versus dual-strand clusters. Genome-wide, piRNA production from dual-strand clusters requires the RDC complex consisting of Rhi, Deadlock (Del), and Cuff. | 24906153 |
2012-01-21 10:19:00 | results unveil a link between Cuff activity, heterochromatin assembly and piRNA cluster expression, which is critical for stem-cell and germ-cell development in Drosophila | 21952049 |
Type | IDs |
---|---|
Synonymous | CG13190, Cuff, Dmel\CG13190 |
Gene |
UniProtKB-ID:
CUFF_DROME
UniprotKB:
Q9V629
UniParc:
UPI0000080D5F
EMBL:
BT024325,
AE013599
EnsemblGenome:
FBgn0260932
KO:
dme:Dmel_CG13190
|
Nucleutide sequences |
EMBL-CDS:
ABC86387.1,
AAF58610.1
Gene_ORFName:
CG13190
EnsemblGenome_TRS:
FBtr0088034
|
Protein sequencees |
EnsemblGenome_PRO:
FBpp0087141
RefSeq:
NP_610709.1
|
Others |
UniRef100:
UniRef100_Q9V629
UniRef90:
UniRef90_Q9V629
UniRef50:
UniRef50_Q9V629
UniGene:
Dm.30905
|
{{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
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Refseq |
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Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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