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36269 cuff

36269

cuff

cutoff

protein-coding

Drosophila melanogaster

基因描述

Type Description
Definition cutoff

研究结论

Date Results Publications
2017-09-23 13:42:00 Results confirm that Cutoff is involved in the transcriptional regulation of piRNA clusters and in the repression of transposable elements in germ cells. Surprisingly, however, Cutoff is found enriched at and affects the expression of other noncoding RNAs, including spliceosomal RNAs and small nucleolar RNAs. Finally, mutations in Cutoff result in the deregulation of hundreds of protein-coding genes in germ cells. 28420675
2017-08-26 12:50:00 Cutoff suppresses RNA polymerase II termination to ensure expression of piRNA precursors. 27292797
2014-08-09 10:27:00 Analysis of piRNA clusters in the Drosophila ovary shows that hallmarks of II (Pol II) transcription are fundamentally different at uni-strand versus dual-strand clusters. Genome-wide, piRNA production from dual-strand clusters requires the RDC complex consisting of Rhi, Deadlock (Del), and Cuff. 24906153
2012-01-21 10:19:00 results unveil a link between Cuff activity, heterochromatin assembly and piRNA cluster expression, which is critical for stem-cell and germ-cell development in Drosophila 21952049

名称对应

Type IDs
Synonymous CG13190, Cuff, Dmel\CG13190
Gene
UniProtKB-ID: CUFF_DROME
UniprotKB: Q9V629
UniParc: UPI0000080D5F
EMBL: BT024325, AE013599
EnsemblGenome: FBgn0260932
KO: dme:Dmel_CG13190
Nucleutide sequences
EMBL-CDS: ABC86387.1, AAF58610.1
Gene_ORFName: CG13190
EnsemblGenome_TRS: FBtr0088034
Protein sequencees
EnsemblGenome_PRO: FBpp0087141
RefSeq: NP_610709.1
Others
UniRef100: UniRef100_Q9V629
UniRef90: UniRef90_Q9V629
UniRef50: UniRef50_Q9V629
UniGene: Dm.30905

全选

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研究热度

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