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36110 trsn

36110

trsn

translin

protein-coding

Drosophila melanogaster

基因描述

Type Description
Definition translin

研究结论

Date Results Publications
2020-05-30 13:15:00 it has been shown that translin is upregulated under starvation conditions in Drosophila and is involved in the integration of sleep and metabolic rate of the flies. 31894120
2019-06-29 10:30:00 Findings indicate that the loss of Translin/TRAX complex (dmC3PO) promoted the accumulation of the passenger strand of esi-2.1 (hp-CG4068B) and increased the accumulation of miR-bantam. 30576408
2016-12-24 11:22:00 Study describes the identification of translin (trsn), a highly conserved RNA/DNA binding protein, as essential for starvation-induced sleep suppression. Strikingly, trsn does not appear to regulate energy stores, free glucose levels, or feeding behavior suggesting the sleep phenotype of trsn mutant flies is not a consequence of general metabolic dysfunction or blunted response to starvation. 27020744
2011-06-25 14:21:00 These studies establish that Trax adopts the translin fold, possesses catalytic centers essential for C3PO's endoRNase activity and interacts extensively with translin to form an octameric assembly. 21552261
2010-01-21 00:00:00 Drosophila translin may have roles in neuronal development and behavior analogous to that of mouse translin. 17275950

名称对应

Type IDs
Synonymous CG11761, Dmel\CG11761, TB-RBP
Gene
UniProtKB-ID: Q7JVK6_DROME
UniprotKB: Q7JVK6
UniParc: UPI000007BA4D
EMBL: AE013599, AY118870
EnsemblGenome: FBgn0033528
KO: dme:Dmel_CG11761
Nucleutide sequences
EMBL-CDS: AAF58784.1, AAM50730.1
Gene_ORFName: CG11761, Dmel_CG11761
EnsemblGenome_TRS: FBtr0088306
Protein sequencees
EnsemblGenome_PRO: FBpp0087398
RefSeq: NP_610591.1
Others
UniRef100: UniRef100_Q7JVK6
UniRef90: UniRef90_Q7JVK6
UniRef50: UniRef50_Q7JVK6
UniGene: Dm.12127

全选

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研究热度

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