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36086 JhI-1

36086

JhI-1

Juvenile hormone-inducible protein 1

protein-coding

Drosophila melanogaster

基因描述

Type Description
Definition Juvenile hormone-inducible protein 1

研究结论

Date Results Publications
2017-10-28 11:29:00 The linker region was explored by Ala-scanning through two conserved regions of D. melanogaster tRNase Z: NdomTprox, located at the carboxy end of the amino domain proximal to the linker, and Tflex, a flexible site in the linker. Periodic substitutions in a hydrophobic patch (F329 and L332) at the carboxy end of NdomTprox show 2,700 and 670-fold impairment relative to wild type 29045449
2016-04-30 11:50:00 The study implicates Drosophila RNase Z(L) in a novel retrograde signaling pathway initiated by the damage in mitochondria and manifested in a cell cycle delay before the mitotic entry. 26553808
2013-11-16 11:20:00 RNase Z(L) activity is essential for all phases of fly development that involve cell division, including growth of adult tissue progenitors during larval and metamorphic stages, and gametogenesis in adults. 23867108
2011-05-28 10:13:00 The study shows that dRNaseZ is necessary for 3'-end processing of nuclear & mitochondrial tRNAs. In mitotically growing imaginal discs it is required for cell proliferation and/or viability. In endoreplicating salivary glands, it controls organ size. 21146608
2010-01-21 00:00:00 Residues in two homology blocks on the amino side of the tRNase Z His domain contribute unexpectedly to pre-tRNA 3' end processing 16618969

名称对应

Type IDs
Synonymous CG3298, Dmel\CG3298, JHI-1, RNZ, dRNase Z, dRNaseZ, dtRNaseZ, jhI-1, tRNAse Z, tRNase Z
Gene
UniProtKB-ID: RNZ_DROME
UniprotKB: Q8MKW7
UniParc: UPI000023B824
EMBL: AE013599, AF215894, AY119279
KO: dme:Dmel_CG3298
Nucleutide sequences
EMBL-CDS: AAF99588.1, AAM68783.1, AAM51139.1
Gene_ORFName: CG3298
Protein sequencees
RefSeq: NP_724916.1
Others
UniRef100: UniRef100_Q8MKW7
UniRef90: UniRef90_Q8MKW7
UniRef50: UniRef50_Q8MKW7
UniGene: Dm.2795

全选

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