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360426 Pla2g6

360426

Pla2g6

phospholipase A2 group VI

protein-coding

Rattus norvegicus

基因描述

Type Description
Definition phospholipase A2 group VI

研究结论

Date Results Publications
2019-04-06 10:58:00 the transcriptional activation of nuclear factor of activated T-cell proteins (NFATs), but not nuclear factor-kappaB, by IL-1beta stimulation was markedly attenuated by the iPLA2 inhibitor bromoenol lactone, and NFATc4 knockdown markedly attenuated the IL-1beta-induced expression of both CCL2 and CXCL10. 29637744
2017-04-08 11:00:00 PEDF can protect against hypoxia-induced activation of the NLRP3 inflammasome by inhibiting mitochondrial fission though PEDFR/iPLA2. 27973457
2016-05-14 11:03:00 Data suggest glucose-induced insulin secretion is first up-regulated (acute infection), then down-regulated (chronic infection) in beta cells infected with S. aureus; Pla2g4a is up-regulated in acute infection; Pla2g6 is up-regulated in chronic infection. 26632509
2016-02-06 11:31:00 The iPLA2gamma/UCP2 synergy provides a feedback antioxidant mechanism preventing oxidative stress by physiological fatty acid intake in pancreatic beta-cells, regulating glucose-, fatty acid-, and redox-stimulated insulin secretion. 25925080
2015-10-31 10:25:00 membrane potential sensitive activity is the iPLA2gamma 26206229

名称对应

Type IDs
Synonymous GVI PLA2, PNPLA9, caI-PLA2, iPLA2-beta, iPla2
Gene
UniProtKB-ID: PLPL9_RAT
UniprotKB: P97570
UniParc: UPI000017E799, UPI000019BD52
EMBL: CH473950, AABR06052011, U51898, BC081916
Ensembl: ENSRNOG00000012295
KO: rno:360426
Nucleutide sequences
EMBL-CDS: EDM15808.1, EDM15809.1, AAC53136.1, AAH81916.1
Ensembl_TRS: ENSRNOT00000087344, ENSRNOT00000017108, ENSRNOT00000090565, ENSRNOT00000016827
Protein sequencees
Ensembl_PRO: ENSRNOP00000016827, ENSRNOP00000017104, ENSRNOP00000075311, ENSRNOP00000072104
RefSeq: XP_006242062.1, NP_001005560.1, XP_006242061.1, XP_017450396.1, XP_006242066.1, NP_001257725.1, XP_006242063.1, XP_006242067.1, XP_006242059.1, XP_006242065.1, XP_008763979.1, XP_006242064.1, XP_006242060.1
Others
UniRef100: UniRef100_P97570
UniRef90: UniRef90_P97570
UniRef50: UniRef50_O60733-2
UniGene: Rn.44692

全选

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