| Type | Description |
|---|---|
| Definition | shroom family member 2 |
| Date | Results | Publications |
|---|---|---|
| 2020-04-11 12:41:00 | SHROOM2 is downregulated in nasopharyngeal carcinoma and is implicated in the suppression of cancer cell invasion and metastasis by preventing EMT, which is largely independent of Rho-ROCK signaling. | 30683844 |
| 2019-05-25 12:06:00 | SHROOM2 deletion is associated with Ocular albinism with infertility and late-onset sensorineural hearing loss. | 30160833 |
| 2019-04-06 11:35:00 | These findings provide genetic and molecular insights into the effects of rare damaging variants in SHROOM2, indicating that such variants of SHROOM2 might contribute to the risk of human Neural tube defects | 29423651 |
| 2012-11-17 10:47:00 | We identified three new CRC risk loci at 6p21 (rs1321311, near CDKN1A; P = 1.14 x 10(-10)), 11q13.4 (rs3824999, intronic to POLD3; P = 3.65 x 10(-10)) and Xp22.2 (rs5934683, near SHROOM2; P = 7.30 x 10(-10)). | 22634755 |
| 2011-07-23 11:33:00 | Data suggest that Shroom2 facilitates the formation of a contractile network within endothelial cells, the loss of which leads to an increase in endothelial sprouting, migration, and angiogenesis. | 21248203 |
| Type | IDs |
|---|---|
| Synonymous | APXL, HSAPXL |
| Gene |
UniProtKB-ID:
SHRM2_HUMAN,
F5H3B6_HUMAN,
Q68DU3_HUMAN,
B7Z682_HUMAN
UniprotKB:
Q13796,
F5H3B6,
Q68DU3,
B7Z682
UniParc:
UPI0004E4C959,
UPI000041A09C,
UPI0000125D05,
UPI0001914DDA
EMBL:
KF458968,
AC090481,
AC135254,
KF458965,
KF458967,
X83543,
BC140866,
KF458973,
AK299907,
AC002365,
CR749271
Ensembl:
ENSG00000146950
KO:
hsa:357
|
| Nucleutide sequences |
EMBL-CDS:
CAA58534.1,
AAI40867.1,
AAC32592.1,
CAH18127.1,
BAH13168.1
Ensembl_TRS:
ENST00000380913,
ENST00000418909
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000370299,
ENSP00000415229
RefSeq:
XP_016884982.1,
NP_001640.1,
XP_005274557.2,
XP_016884981.1,
NP_001307592.1,
NP_001307593.1,
XP_011543808.1,
XP_016884983.1
|
| Others |
UniRef100:
UniRef100_F5H3B6,
UniRef100_Q68DU3,
UniRef100_Q13796,
UniRef100_B7Z682
UniRef90:
UniRef90_Q13796,
UniRef90_A0A2K6F644
UniRef50:
UniRef50_Q13796,
UniRef50_A0A2K6F644
UniGene:
Hs.567236
CCDS:
CCDS14135.1
|
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|---|---|---|---|---|---|---|---|---|
| Refseq |
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