| Type | Description |
|---|---|
| Definition | Growth arrest and DNA damage-inducible 45 |
| Date | Results | Publications |
|---|---|---|
| 2020-02-15 12:32:00 | D-GADD45 is required for proper regeneration of wing imaginal discs. Findings demonstrate that a tight regulation of D-GADD45 levels is required for its correct function both, in development and during the stress response after cell death. | 31109086 |
| 2017-11-18 13:46:00 | These findings demonstrate that degradation of Gadd45 mRNA is the essential nonsense-mediated mRNA decay function and, surprisingly, that the surveillance of abnormal mRNAs by this pathway is not necessarily required for viability. | 26952209 |
| 2016-03-26 10:21:00 | Overexpression of D-GADD45 in the Drosophila nervous system prolongs the median and maximum life span without deterioration of quality of life parameters. | 22803081 |
| 2015-10-03 10:22:00 | D-GADD45 overexpression in the nervous system is associated with delayed neurodegeneration. | 25252831 |
| 2013-05-04 12:33:00 | D-GADD45 expression is activated by most of the studied stress factors, and D-GADD45 overexpression resulted in an increase of stress resistance. | 23095639 |
| Type | IDs |
|---|---|
| Synonymous | BcDNA:RH70774, CG11086, D-GADD45, Dmel\CG11086, GADD45, GG1086 |
| Gene |
UniProtKB-ID:
A1Z6W5_DROME
UniprotKB:
A1Z6W5
UniParc:
UPI0000075A6B
EMBL:
AE013599,
BT088861
EnsemblGenome:
FBgn0033153
KO:
dme:Dmel_CG11086
|
| Nucleutide sequences |
EMBL-CDS:
AAF59278.1,
ACS78061.1
Gene_ORFName:
Dmel_CG11086,
CG11086
EnsemblGenome_TRS:
FBtr0089049
|
| Protein sequencees |
EnsemblGenome_PRO:
FBpp0088120
RefSeq:
NP_610264.1
|
| Others |
UniRef100:
UniRef100_A1Z6W5
UniRef90:
UniRef90_A1Z6W5
UniRef50:
UniRef50_A1Z6W5
UniGene:
Dm.12137
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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