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34881 Su(H)

34881

Su(H)

Suppressor of Hairless

protein-coding

Drosophila melanogaster

基因描述

Type Description
Definition Suppressor of Hairless

研究结论

Date Results Publications
2020-08-12 11:19:00 RBPJ protein stability depends on protein complex formation with either H or NICD, similar to Su(H), demonstrating that the murine homologue underlies the same regulatory mechanisms as Su(H) in Drosophila. These results underscore the importance of regulating the availability of RBPJ protein to correctly mediate Notch signaling activity in the fly. 31615108
2019-08-24 11:49:00 Study shows that Drosophila Notch/Su(H) signaling and the secreted fibrinogen-related protein Scabrous in mushroom body memory circuitry are important for the enduring preference of cues associated with alcohol's rewarding properties. 30482693
2019-06-29 11:04:00 Phosphorylation of Suppressor of Hairless impedes its DNA-binding activity. 28928428
2018-06-30 11:34:00 complex genetic interactions of novel alleles deficient in co-repressor binding 29509808
2017-12-23 11:05:00 Structural models show that the Hairless-Su(H) repressor complexes from Daphnia and Drosophila are almost indistinguishable from one another. Amino acid residues in direct contact within the Hairless-Su(H) complex are at absolutely identical positions in the two homologues. 28861687

名称对应

Type IDs
Synonymous BG:DS00929.10, C, CBF1, CG3497, CSL, D, Dmel\CG3497, E(H), FTZ-F2, RBJK_DROME, RBP-J kappa, RBP-J[[Kappa]], RBP-Jkappa, SU(H), SUH, Su(h), SuH, Su_H, anon-WO0257455.3, br7, dCSL, dRBP-JK, dRBP-J[[Kappa]], dRBP-Jk, l(1)br7, l(2)35Bh, l(2)br7, l(2)k07904, oss, su(H)
Gene
UniProtKB-ID: SUH_DROME, X2JAI1_DROME
UniprotKB: P28159, X2JAI1
UniParc: UPI000004DC83
EMBL: AF088261, S69213, AF088274, AF088262, AF088270, AF088267, AF088256, AE014134, AF088259, AF088266, AF088268, M94383, AF088271, AY069091, AF088265, AF088272, AF088260, AF088264, AF088255, AF088257, X58393, AF088273, AF088263, AF088258, AF088269
EnsemblGenome: FBgn0004837
KO: dme:Dmel_CG3497
Nucleutide sequences
EMBL-CDS: AAD39703.1, CAA41282.1, AAD39698.1, AAD39712.1, AAA06211.1, AAD39709.1, AAD39717.1, AAD39714.1, AAD39705.1, AAA28919.1, AAD39704.1, AAD39708.1, AAD39700.1, AAD39702.1, AAD39701.1, AAD39713.1, AAL39236.1, AAD39716.1, AAD39710.1, AAF53434.1, AAD39707.1, AAD39711.1, AAD39706.1, AAD39715.1, AAD39699.1, AHN54462.1
Gene_ORFName: CG3497, Dmel_CG3497, CG3497
EnsemblGenome_TRS: FBtr0080700, FBtr0346621, FBtr0346621, FBtr0080700
Protein sequencees
EnsemblGenome_PRO: FBpp0312201, FBpp0080261, FBpp0080261, FBpp0312201
RefSeq: NP_476868.1, NP_001285948.1
Others
UniRef100: UniRef100_P28159
UniRef90: UniRef90_P28159
UniRef50: UniRef50_P28159
UniGene: Dm.2288

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