| Type | Description |
|---|---|
| Definition | lethal (2) giant discs 1 |
| Date | Results | Publications |
|---|---|---|
| 2020-10-24 14:13:00 | Unravelling of Hidden Secrets: The Lethal (2) Giant Discs (Lgd)/CC2D1, Notch Signalling and Cancer. | 33034024 |
| 2018-03-10 10:53:00 | Lgd regulates ESCRT activity by controlling access to the Shrub self-assembly surface. | 28564595 |
| 2016-02-20 10:12:00 | During oogenesis lgd loss of function causes ectopic activation of the Drosophila BMP signalling pathway. | 25804739 |
| 2014-02-22 10:42:00 | lgd cells have a defect that delays degradation of transmembrane proteins, which are residents of the plasma membrane. Furthermore, our results show that the activation of Notch in lgd cells occurs in the lysosome. | 23178945 |
| 2012-09-08 10:30:00 | genetic studies indicate that the activation of Notch in ESCRT and lgd mutant cells occurs in a different manner and that the activity of Shrub and other ESCRT components are required for the activation of Notch in lgd mutant cells | 22389409 |
| Type | IDs |
|---|---|
| Synonymous | CG4713, Dmel\CG4713, SH495, gd, l(2)SH0495, l(2)SH2 0495, l(2)gd, l(2)giant disc, l[[2]]gd, lgd |
| Gene |
UniProtKB-ID:
C2D1_DROME,
M9NEZ0_DROME
UniprotKB:
Q9VKJ9,
M9NEZ0
UniParc:
UPI000007DA36,
UPI000237F422
EMBL:
AE014134,
AY058523
EnsemblGenome:
FBgn0261983
KO:
dme:Dmel_CG4713
|
| Nucleutide sequences |
EMBL-CDS:
AAL13752.1,
AAF53069.1,
AFH03650.1
Gene_ORFName:
CG4713,
CG4713,
Dmel_CG4713
EnsemblGenome_TRS:
FBtr0080197,
FBtr0306138
|
| Protein sequencees |
EnsemblGenome_PRO:
FBpp0079786,
FBpp0297275
RefSeq:
NP_001245976.1,
NP_609488.1
|
| Others |
UniRef100:
UniRef100_M9NEZ0,
UniRef100_Q9VKJ9
UniRef90:
UniRef90_Q9VKJ9
UniRef50:
UniRef50_Q9VKJ9
UniGene:
Dm.4175
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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